ReviewEnvironmental health and preventive medicine2021
Influence of height on endothelial maintenance activity: a narrative review.
Review in Environmental health and preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Anti-early antigen Epstein-Barr virus titer and atherosclerosis in relation to vascular endothelial growth factor (VEGF) polymorphism rs3025039 among older Japanese individuals.Environmental health and preventive medicine · 2025Article
- Subclinical hypothyroidism and height loss according to free thyroxine levels: a prospective study.Environmental health and preventive medicine · 2025Article
- Beneficial influence of low-density lipoprotein cholesterol on the endothelium in relation to endothelial repair.Environmental health and preventive medicine · 2025Article
- Article
- Association between serum uric acid levels and cardio-ankle vascular index stratified by circulating level of CD34-positive cells among elderly Japanese men: a cross-sectional study.Scientific reports · 2024Article
- Association between eating speed and atherosclerosis in relation to growth differentiation factor-15 levels in older individuals in a cross-sectional study.Scientific reports · 2024Article
- Association between atherosclerosis and height loss among older individuals.Scientific reports · 2024Article
- Association between serum albumin levels and height loss in Japanese workers: a retrospective study.Journal of physiological anthropology · 2023Article
- Progression of Carotid Intima-Media Thickness Partly Indicates the Prevention of Hypertension among Older Individuals in the General Population.Life (Basel, Switzerland) · 2023Article
- Serum Concentration of Growth Differentiation Factor 15 and Atherosclerosis among General Older Japanese Individuals with Normal Weight.Biomedicines · 2023Article
- Low-Density Lipoprotein Cholesterol, Structural Atherosclerosis, and Functional Atherosclerosis in Older Japanese.Nutrients · 2022Article
- Mechanism underlying vascular remodeling in relation to circulating CD34-positive cells among older Japanese men.Scientific reports · 2022Article
- Height and Active Arterial Wall Thickening in Relation to Thyroid Cysts Status among Elderly Japanese: A Prospective Study.Biology · 2022Article
- VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study.Bioengineering (Basel, Switzerland) · 2022Article
- Tooth Loss and Carotid Intima-Media Thickness in Relation to Functional Atherosclerosis: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Association between circulating CD34-positive cell count and height loss among older men.Scientific reports · 2022Article
- Vascular endothelial growth factor (VEGF) polymorphism rs3025039 and atherosclerosis among older with hypertension.Scientific reports · 2022Article
- Does body height affect vascular function?Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Short stature is associated with low flow-mediated vasodilation in Japanese men.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Association between height-related polymorphism rs17081935 and reduced handgrip strength in relation to status of atherosclerosis: a cross-sectional study.Environmental health and preventive medicine · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Recent studies have revealed an inverse association between height and cardiovascular disease. However, the background mechanism of this association has not yet been clarified. Height has also been reported to be positively associated with cancer. Therefore, well-known cardiovascular risk factors, such as increased oxidative stress and chronic inflammation, are not the best explanations for this inverse association because these risk factors are also related to cancer. However, impaired blood flow is the main pathological problem in cardiovascular disease, while glowing feeding vessels (angiogenesis) are the main characteristic of cancer pathologies. Therefore, endothelial maintenance activity, especially for the productivity of hematopoietic stem cells such as CD34-positive cells, could be associated with the height of an individual because this cell contributes not only to the progression of atherosclerosis but also to the development of angiogenesis. In addition, recent studies have also revealed a close connection between bone marrow activity and endothelial maintenance; bone marrow-derived hematopoietic stem cells contribute towards endothelial maintenance. Since the absolute volume of bone marrow is positively associated with height, height could influence endothelial maintenance activity. Based on these hypotheses, we performed several studies. The aim of this review is not only to discuss the association between height and bone marrow activity, but also to describe the potential mechanism underlying endothelial maintenance. In addition, this review also aims to explain some of the reasons that implicate hypertension as a major risk factor for stroke among the Japanese population. The review also aims to clarify the anthropological reasons behind the high risk of atherosclerosis progression in Japanese individuals with acquired genetic characteristics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.