Evidence map›Paper›PMID 33548303›Full record

Trial reportJournal of the American Academy of Dermatology2021

Topical timolol 0.5% gel-forming solution for erythema in rosacea: A quantitative, split-face, randomized, and rater-masked pilot clinical trial.

Jerry Tsai, Anna L Chien, Noori Kim, Saleh Rachidi, Brian M Connolly, Hester Lim, Sabrina Sisto Alessi César, Sewon Kang, Luis A Garza

Registry-linked trialOpen access · bronzeAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Academy of Dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02774590 (Timolol for the Treatment of Acne and Rosacea), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02774590 phase1completednot on this map

Timolol for the Treatment of Acne and Rosacea

TypeinterventionalSponsorJohns Hopkins UniversityRan2016 to 2021Enrolled8ConditionsAcne Vulgaris, RosaceaArmsTimolol
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Rosacea: Pathogenesis and Therapeutic Correlates.Journal of cutaneous medicine and surgery
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jerry TsaiDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Anna L ChienDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Noori KimDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Saleh RachidiDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Brian M ConnollyDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Hester LimDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sabrina Sisto Alessi CésarDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sewon KangDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Luis A GarzaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: LAG@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Retinoic acid synthesis induced by noncoding dsRNA controls RegenerationR01AR074846 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2019 to 2023
$2.3M
NIAMS NIH HHS R01 AR074846
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

RosaceaTimololDouble-Blind MethodErythemaGelsHumansResearch DesignTreatment OutcomeGelsTimolol

Identifiers

PMID33548303
PMCPMC8329126
OpenAlexW3127866570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.