ArticleCell host & microbe2021
The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs.
Article in Cell host & microbe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 42 citations in OpenAlex.
- Chromatin accessibility and histone landscapes define immune signal-specific transcriptional reprogramming inaBIOTECH · 2026Article
- Epigenetic regulation of TaFIP phytocytokine clusters confers basal resistance via receptor kinase TaFIPR in wheat.Nature plants · 2026Article
- TIR innovations in plant immunity.The New phytologist · 2026Review
- Chromatin Remodeler TaSWI3D Controls Wheat Susceptibility to Pathogenic FungusMicroorganisms · 2025Article
- BAF60/SWP73 subunits define subclasses of SWI/SNF chromatin remodelling complexes in Arabidopsis.The New phytologist · 2025Article
- Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025Review
- Wheat Chromatin Remodeling Protein TaSWP73 Contributes to Compatible Wheat-Powdery Mildew Interaction.International journal of molecular sciences · 2025Article
- Redox-inactive CC-type glutaredoxins interfere with TGA transcription factor-dependent repression of target promoters in roots.The Plant cell · 2025Article
- Reversible ubiquitination conferred by domain shuffling controls paired NLR immune receptor complex homeostasis in plant immunity.Nature communications · 2025Article
- Alternative splicing of a potato disease resistance gene maintains homeostasis between growth and immunity.The Plant cell · 2024Article
- The cap-binding complex modulates ABA-responsive transcript splicing during germination in barley (Hordeum vulgare).Scientific reports · 2024Article
- Loss of cold tolerance is conferred by absence of the WRKY34 promoter fragment during tomato evolution.Nature communications · 2024Article
- Review
- Organization, genomic targeting, and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis.The Plant cell · 2023Article
- Transcriptional regulation of plant innate immunity.Essays in biochemistry · 2022Review
- Alternative splicing as a key player in the fine-tuning of the immunity response in Arabidopsis.Molecular plant pathology · 2022Review
- Molecular innovations in plant TIR-based immunity signaling.The Plant cell · 2022Review
- Life-or-death decisions in plant immunity.Current opinion in immunology · 2022Review
- CaSWC4 regulates the immunity-thermotolerance tradeoff by recruiting CabZIP63/CaWRKY40 to target genes and activating chromatin in pepper.PLoS genetics · 2022Article
- Histone modification and chromatin remodeling in plant response to pathogens.Frontiers in plant science · 2022Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
In both plant and animal innate immune responses, surveillance of pathogen infection is mediated by membrane-associated receptors and intracellular nucleotide-binding domain and leucine-rich-repeat receptors (NLRs). Homeostasis of NLRs is under tight multilayered regulation to avoid over-accumulation or over-activation, which often leads to autoimmune responses that have detrimental effects on growth and development. How NLRs are regulated epigenetically at the chromatin level remains unclear. Here, we report that SWP73A, an ortholog of the mammalian switch/sucrose nonfermentable (SWI/SNF) chromatin-remodeling protein BAF60, suppresses the expression of NLRs either directly by binding to the NLR promoters or indirectly by affecting the alternative splicing of some NLRs through the suppression of cell division cycle 5 (CDC5), a key regulator of RNA splicing. Upon infection, bacteria-induced small RNAs silence SWP73A to activate a group of NLRs and trigger robust immune responses. SWP73A may function as a H3K9me2 reader to enhance transcription suppression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.