Evidence map›Paper›PMID 33548173›Full record

ReviewNeuron2021

Unraveling circuits of visual perception and cognition through the superior colliculus.

Michele A Basso, Martha E Bickford, Jianhua Cang

Abstract readReview
In one paragraph

Review in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. A collicular-hypothalamic pathway for social visual awareness.bioRxiv : the preprint server for biology · 2026
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63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michele A BassoFuster Laboratory of Cognitive Neuroscience, Department of Psychiatry and Biobehavioral Sciences, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: mbasso@mednet.ucla.edu.
Martha E BickfordUniversity of Louisville, Louisville, KY, USA.
Jianhua CangUniversity of Virginia, Charlottesville, VA, USA.

Funding

WaNPRC Macaca nemestrina SPF Breeding ColonyU42OD011123 · OD · UNIVERSITY OF WASHINGTON · PI CHARLOTTE HOTCHKISS · 2012 to 2026
$34.4M
Visual Target Selection for Saccadic Eye MovementsR01EY013692 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI BASSO, MICHELE A · 2002 to 2021
$7.0M
Neural Mechanisms of Stereoscopic VisionR01EY020950 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2010 to 2026
$5.9M
Visual Signal Transformation in the Retinocollicular PathwayR01EY026286 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2016 to 2026
$4.4M
Changes across the lifespan in the use of heuristics to guide decision-makingR01AG063090 · NIA · UNIVERSITY OF WASHINGTON · PI BASSO, MICHELE A · 2019 to 2023
$3.8M
An Open Source, Wireless, Miniature Microscope for Monitoring Neuronal ActivityUF1NS107668 · NINDS · UNIVERSITY OF WASHINGTON · PI BASSO, MICHELE A, GOLSHANI, PEYMAN · 2018 to 2018
$3.7M
An in vitro model of saccadic eye movement choiceR01EY019663 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI BASSO, MICHELE A · 2010 to 2019
$3.5M
Parallel Tectothalamic PathwaysR01EY024173 · NEI · UNIVERSITY OF LOUISVILLE · PI BICKFORD, MARTHA E, GUIDO, WILLIAM · 2014 to 2019
$2.7M
Parallel Pulvinar PathwaysR01EY031322 · NEI · UNIVERSITY OF LOUISVILLE · PI BICKFORD, MARTHA E, GUIDO, WILLIAM · 2020 to 2023
$1.9M
Visual Target Selection for Saccadic Eye MovementsR56EY013692 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI BASSO, MICHELE A · 2007 to 2007
$352k
NEI NIH HHS R01 EY013692NEI NIH HHS R01 EY019663NEI NIH HHS R01 EY020950NEI NIH HHS R01 EY024173NEI NIH HHS R01 EY026286NEI NIH HHS R01 EY031322NEI NIH HHS R56 EY013692NIA NIH HHS R01 AG063090NIH HHS U42 OD011123NINDS NIH HHS UF1 NS107668
6 · The paper itself

Abstract

The superior colliculus is a conserved sensorimotor structure that integrates visual and other sensory information to drive reflexive behaviors. Although the evidence for this is strong and compelling, a number of experiments reveal a role for the superior colliculus in behaviors usually associated with the cerebral cortex, such as attention and decision-making. Indeed, in addition to collicular outputs targeting brainstem regions controlling movements, the superior colliculus also has ascending projections linking it to forebrain structures including the basal ganglia and amygdala, highlighting the fact that the superior colliculus, with its vast inputs and outputs, can influence processing throughout the neuraxis. Today, modern molecular and genetic methods combined with sophisticated behavioral assessments have the potential to make significant breakthroughs in our understanding of the evolution and conservation of neuronal cell types and circuits in the superior colliculus that give rise to simple and complex behaviors.

Indexed as

AnimalsCognitionHumansNeural PathwaysSuperior ColliculiVisual Perceptionactionadaptationattentionavoidanceconservationdecision-makingdefensive behaviorsescape behaviorsevolutionlaminationmotor mapsneural cartographyoptic tectumorientingprey capturesensory mapsvision

Identifiers

PMID33548173
PMCPMC7979487

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.