Evidence map›Paper›PMID 33547673›Full record

ArticleMagnetic resonance in medicine2021

Temperature-based MRI safety simulations with a limited number of tissues.

Giuseppe Carluccio, Can Akgun, John Thomas Vaughan, Christopher Collins

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Giuseppe CarluccioDepartment of Radiology, New York University School of Medicine, New York, New York, USA.ORCID 0000-0001-5376-3843
Can AkgunFlywheel Exchange, Minneapolis, Minnesota, USA.
John Thomas VaughanDepartment of Biomedical Engineering, Department of Radiology, Columbia University, New York, New York, USA.
Christopher CollinsDepartment of Radiology, New York University School of Medicine, New York, New York, USA.
New York University · USColumbia University · USScience Exchange (United States) · US

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dmitry S Novikov · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

purposeDemonstrate ability to produce reasonable simulations of temperature using numerical models of the human body with a limited number of tissues.

methodsFor both a male and female human body model, numerical simulations were used to calculate temperature distributions in three different models of the same human body: the original model with 35 tissues for the male model and 76 tissues for the female model, a simplified model having only three tissues (muscle, fat, and lung), and a simplified model having six tissues (muscle, fat, lung, bone, brain, and skin).

resultsAlthough a three-tissue model gave reasonable specific absorption rate estimates in comparison to an original with many more tissues, because of tissue-specific thermal and physiological properties that do not affect specific absorption rate, such as rate of perfusion by blood, the three-tissue model did not provide temperature distributions similar to those of the original model. Inclusion of a few additional tissues, as in the six-tissue model, produced results in much better agreement with those from the original model.

conclusionReasonable estimates of temperature can be simulated with a limited number of tissues, although this number is higher than the number of tissues required to produce reasonable simulations of specific absorption rate. For exposures primarily in the head and thorax, six tissues may be adequate for reasonable estimates of temperature.

Indexed as

HeadMagnetic Resonance ImagingBrainComputer SimulationFemaleHumansMaleModels, BiologicalPerfusionTemperatureMRIsafetySARsimulationtemperature

Identifiers

PMID33547673
PMCPMC8193628
OpenAlexW3128539165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.