Evidence map›Paper›PMID 33547619›Full record

ArticleMolecular diversity2022

Synthesis, molecular docking studies, and in vitro antimicrobial evaluation of piperazine and triazolo-pyrazine derivatives.

Mahadev Patil, Anurag Noonikara-Poyil, Shrinivas D Joshi, Shivaputra A Patil, Siddappa A Patil, Abby M Lewis, Alejandro Bugarin

Abstract read
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Article in Molecular diversity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahadev PatilCentre for Nano and Material Sciences, Jain University, Jain Global Campus, Bangalore, 562112, Karnataka, India.
Anurag Noonikara-PoyilDepartment of Chemistry and Biochemistry, University of Texas At Arlington, Arlington, TX, 76019, USA.
Shrinivas D JoshiNovel Drug Design and Discovery Laboratory, Department of Pharmaceutical Chemistry, S. E. T's College of Pharmacy, Sangolly Rayanna Nagar, Dharwad, 580 002, Karnataka, India.
Shivaputra A PatilPharmaceutical Sciences Department, College of Pharmacy, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL, 60064, USA.
Siddappa A PatilCentre for Nano and Material Sciences, Jain University, Jain Global Campus, Bangalore, 562112, Karnataka, India. p.siddappa@jainuniversity.ac.in.
Abby M LewisDepartment of Chemistry and Physics, Florida Gulf Coast University, Fort Myers, FL, 33965, USA.
Alejandro BugarinDepartment of Chemistry and Physics, Florida Gulf Coast University, Fort Myers, FL, 33965, USA. abugarin@fgcu.edu.ORCID http://orcid.org/0000-0001-8504-355X

Funding

American Chemical Society Petroleum Research Fund 58269-ND1
6 · The paper itself

Abstract

For this work, two series of new piperazine derivatives (3a-o) and triazolo-pyrazine derivatives (3p-t) were synthesized in a single-step reaction. All twenty adducts were obtained in good to high yields and fully characterized by

Indexed as

Anti-Infective AgentsPyrazinesAnti-Bacterial AgentsMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructurePiperazineStructure-Activity RelationshipAnti-Bacterial AgentsAnti-Infective AgentsPiperazinePyrazinesAntimicrobial activityMolecular dockingPiperazine derivativesSynthesisTriazolo-pyrazine

Identifiers

PMID33547619

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.