ArticleEuropean radiology2021
CT perfusion in peripheral arterial disease-hemodynamic differences before and after revascularisation.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Quantification of Skeletal Muscle Perfusion in Peripheral Artery Disease UsingJournal of the American Heart Association · 2024Trial
- Blood oxygenation level-dependent MRI in critical limb-threatening ischemia: association with clinical and angiographic findings and response to revascularization.Japanese journal of radiology · 2026Article
- Quantifying lower extremity blood flow using low-dose CT perfusion: validation in a swine model.Radiology advances · 2024Article
- Multi-modality imaging for assessment of the microcirculation in peripheral artery disease: Bench to clinical practice.American heart journal plus : cardiology research and practice · 2024Article
- Association of lower extremity peripheral arterial disease with quantitative muscle features from computed tomography angiography.Insights into imaging · 2024Article
- An Overview of Clinical Examinations in the Evaluation and Assessment of Arterial and Venous Insufficiency Wounds.Diagnostics (Basel, Switzerland) · 2023Review
- Contrast-free ultrasound imaging for blood flow assessment of the lower limb in patients with peripheral arterial disease: a feasibility study.Scientific reports · 2023Article
- Approaches to Peripheral Artery Disease in Diabetes: Are There Any Differences?International journal of environmental research and public health · 2022Review
- Clinical Outcomes after Endovascular Revascularisation of the Femoropopliteal Arterial Segment in Patients with Anticoagulant versus Antiplatelet Therapy: A Single-Centre Retrospective Cohort Study.Journal of cardiovascular development and disease · 2022Article
- Impaired pedal arch affects the treatment effect in patients with single tibial artery revascularization demonstrated by intraoperative perfusion.Quantitative imaging in medicine and surgery · 2022Article
- Acute and Long-Term Consequences of COVID-19 on Arterial Stiffness-A Narrative Review.Life (Basel, Switzerland) · 2022Review
- Review
- A Reperfusion BOLD-MRI Tissue Perfusion Protocol Reliably Differentiate Patients with Peripheral Arterial Occlusive Disease from Healthy Controls.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of this study was the assessment of volumetric CT perfusion (CTP) of the lower leg musculature in patients with symptomatic peripheral arterial disease (PAD) before and after interventional revascularisation.
methodsTwenty-nine consecutive patients with symptomatic PAD of the lower extremities requiring interventional revascularisation were assessed prospectively. All patients underwent a CTP scan of the lower leg, and hemodynamic and angiographic assessment, before and after intervention. Ankle-brachial pressure index (ABI) was determined. CTP parameters were calculated with a perfusion software, acting on a no outflow assumption. A sequential two-compartment model was used. Differences in CTP parameters were assessed with non-parametric tests.
resultsThe cohort consisted of 24 subjects with an occlusion, and five with a high-grade stenosis. The mean blood flow before/after (BFpre and BFpost, respectively) was 7.42 ± 2.66 and 10.95 ± 6.64 ml/100 ml*min
conclusionsCTP seems feasible for assessing hemodynamic differences in calf muscles before and after revascularisation in patients with symptomatic PAD. We could show that CTP parameters BF and BV are significantly increased after revascularisation of the symptomatic limb. In the future, this quantitative method might serve as a non-invasive method for surveillance and therapy control of patients with peripheral arterial disease. KEY POINTS: • CTP imaging of the lower limb in patients with symptomatic PAD seems feasible for assessing hemodynamic differences before and after revascularisation in PAD patients. • This quantitative method might serve as a non-invasive method, for surveillance and therapy control of patients with PAD.
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