Evidence map›Paper›PMID 33547478›Full record

ArticleEuropean radiology2021

Evaluation of microvascular permeability of skeletal muscle and texture analysis based on DCE-MRI in alloxan-induced diabetic rabbits.

Baiyu Liu, Lei Hu, Li Wang, Dong Xing, Lin Peng, Pianpian Chen, Feifei Zeng, Weiyin Vivian Liu, Huan Liu, Yunfei Zha

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Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Baiyu LiuDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Lei HuDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Li WangDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Dong XingDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Lin PengDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Pianpian ChenDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Feifei ZengDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Weiyin Vivian LiuMR Research, GE Healthcare, Beijing, 100176, China.
Huan LiuGE Healthcare, Shanghai, 201203, China.
Yunfei ZhaDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. zhayunfei999@126.com.ORCID http://orcid.org/0000-0002-8714-7472
Wuhan University · CNUnited Imaging Healthcare (China) · CN

Funding

National Natural Science Foundation of China 81801670National Natural Science Foundation of China 81871332
6 · The paper itself

Abstract

objectivesTo estimate the microvascular permeability and perfusion of skeletal muscle by using quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and explore the feasibility of using texture analysis (TA) to evaluate subtle structural changes of diabetic muscles.

methodsTwenty-four rabbits were randomly divided into diabetic (n = 14) and control (n = 10) groups, and underwent axial DCE-MRI of the multifidus muscle (0, 4, 8, 12, and 16 weeks after alloxan injection). The pharmacokinetic model was used to calculate the permeability parameters; texture parameters were extracted from volume transfer constant (K

resultsIn the diabetic group, K

conclusionsQuantitative DCE-MRI can be used to evaluate microvascular permeability and perfusion in diabetic skeletal muscle at an early stage; TA based on K KEY POINTS: • Four quantitative parameters of DCE-MRI can be used to evaluate microvascular permeability and perfusion of skeletal muscle in diabetic models at early stages. • Texture analysis based on K

Indexed as

Contrast MediaDiabetes MellitusAlloxanAnimalsCapillary PermeabilityMagnetic Resonance ImagingMuscle, SkeletalRabbitsAlloxanContrast MediaDiabetes mellitusMagnetic resonance imagingMusclesPerfusionPermeability

Identifiers

PMID33547478
OpenAlexW3126387339

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.