Evidence map›Paper›PMID 33547341›Full record

ArticleScientific reports2021

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

Anikó Rátkai, Krisztián Tárnok, Hajar El Aouad, Brigitta Micska, Katalin Schlett, Attila Szücs

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

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  9. Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modeling.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anikó RátkaiDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Krisztián TárnokDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Hajar El AouadDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Brigitta MicskaDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Katalin SchlettDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary. schlett.katalin@ttk.elte.hu.
Attila SzücsDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary. attila.szucs@ttk.elte.hu.
Eötvös Loránd University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homeostatic plasticity stabilizes neuronal networks by adjusting the responsiveness of neurons according to their global activity and the intensity of the synaptic inputs. We investigated the homeostatic regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) and T-type calcium (Ca

Indexed as

Action PotentialsAnimalsCalcium Channels, T-TypeCell Culture TechniquesCells, CulturedHippocampusMiceNeuronsCacna1g protein, mouseCacna1h protein, mouseCacna1i protein, mouseCalcium Channels, T-Type

Identifiers

PMID33547341
PMCPMC7864958
OpenAlexW3127573614

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.