Evidence map›Paper›PMID 33547274›Full record

ArticleTranslational psychiatry2021

Adenosine A

Antonella Ferrante, Zaira Boussadia, Antonella Borreca, Cinzia Mallozzi, Giorgia Pedini, Laura Pacini, Antonella Pezzola, Monica Armida, Fabrizio Vincenzi, Katia Varani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Neoantigen mRNA vaccines and AHuman vaccines & immunotherapeutics · 2025
    Review
  3. Article
  4. Upregulation of adenosine AMolecular psychiatry · 2025
    Article
  5. Article
  6. Article
  7. Adenosine ABiomolecules · 2023
    Article
  8. Article
  9. Article
  10. Chemobrain: An accelerated aging process linking adenosine AInternational review of neurobiology · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Antonella Ferrante *National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Zaira Boussadia *National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.ORCID http://orcid.org/0000-0001-6578-4561
Antonella BorrecaInstitute of Neuroscience (IN)-CNR, Milan, Italy.
Cinzia MallozziDepartment of Neuroscience, Istituto Superiore di Sanità, Rome, Italy.ORCID http://orcid.org/0000-0002-6126-9500
Giorgia PediniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Laura PaciniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Antonella PezzolaNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Monica ArmidaNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Fabrizio VincenziDepartment of Morphology, Surgery and Experimental Medicine, Pharmacology Section, University of Ferrara, Ferrara, Italy.
Katia VaraniDepartment of Morphology, Surgery and Experimental Medicine, Pharmacology Section, University of Ferrara, Ferrara, Italy.
Claudia BagniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.ORCID http://orcid.org/0000-0002-4419-210X
Patrizia PopoliNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Alberto MartireNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy. alberto.martire@iss.it.ORCID http://orcid.org/0000-0003-0538-4704
Istituto Superiore di Sanità · ITUniversity of Rome Tor Vergata · ITUniversity of Ferrara · ITHumanitas University · IT

Funding

Fondazione Telethon (Telethon Foundation) GGP15257FRAXA Research Foundation (FRAXA Research Foundation, Inc.) 349
6 · The paper itself

Abstract

In fragile X syndrome (FXS) the lack of the fragile X mental retardation protein (FMRP) leads to exacerbated signaling through the metabotropic glutamate receptors 5 (mGlu5Rs). The adenosine A

Indexed as

Fragile X SyndromeReceptor, Adenosine A2AAdenosineAnimalsCognitionDisease Models, AnimalFragile X Messenger Ribonucleoprotein 1HippocampusMiceMice, Inbred C57BLMice, KnockoutAdenosineFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Receptor, Adenosine A2A

Identifiers

PMID33547274
PMCPMC7864914
OpenAlexW3127896523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.