Evidence map›Paper›PMID 33547209›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

First-in-Humans Application of

Richard P Baum, Aviral Singh, Harshad R Kulkarni, Peter Bernhardt, Tobias Rydén, Christiane Schuchardt, Nadezda Gracheva, Pascal V Grundler, Ulli Köster, Dirk Müller and 5 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07404176 (Terbium-161 DOTATATE in Metastatic Neuroendocrine Tumors), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07404176 phase2recruitingnot on this mapstarted 2026, after this paper: background citation

Terbium-161 DOTATATE in Metastatic Neuroendocrine Tumors: Assessment of Safety and Efficacy

TypeinterventionalSponsorTata Memorial HospitalRan2026 to 2029Enrolled20ConditionsNeuroendocrine Neoplasms (Tumours), Neuroendocrine Tumors, Metastatic Neuroendocrine TumorsArmsTerbium 161
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. [EJNMMI research · 2026
    Article
  3. Article
  4. Review
  5. Observational
  6. QuantitativeEJNMMI physics · 2026
    Article
  7. Comparative theranostic efficacy ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  8. [Pharmaceutics · 2026
    Article
  9. Article
  10. Head-to-head comparison of [EJNMMI research · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Materials (Basel, Switzerland) · 2025
    Article
  17. Review
  18. Pilot experience of [Theranostics · 2025
    Observational
  19. Quantitative SPECT imaging ofEJNMMI physics · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 6 countries.

Richard P BaumTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany; baum@curanosticum.de cristina.mueller@psi.ch.
Aviral SinghTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Harshad R KulkarniTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Peter BernhardtDepartment of Radiation Physics, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Tobias RydénDepartment of Radiation Physics, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Christiane SchuchardtTheranostics Center for Molecular Radiotherapy and Precision Oncology, ENETS Center of Excellence, Zentralklinik Bad Berka, Bad Berka, Germany.
Nadezda GrachevaCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland.
Pascal V GrundlerCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland.
Ulli KösterInstitut Laue Langevin, Grenoble, France.
Dirk MüllerDepartment of Radiopharmacy, Zentralklinik Bad Berka, Bad Berka, Germany.
Michael PröhlDepartment of Radiopharmacy, Zentralklinik Bad Berka, Bad Berka, Germany.
Jan Rijn ZeevaartRadiochemistry, South African Nuclear Energy Corporation (Necsa), Pelindaba, South Africa.
Roger SchibliCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland.
Nicholas P van der MeulenCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland.
Cristina MüllerCenter for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland; baum@curanosticum.de cristina.mueller@psi.ch.
Zentralklinik Bad Berka · DEPaul Scherrer Institute · CHUniversity of Gothenburg · SEETH Zurich · CHInstitut Laue-Langevin · FRMaastricht University · NLSouth African Nuclear Energy Corporation (South Africa) · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Feasibility StudiesOctreotideAdultAgedHumansMaleNeuroendocrine TumorsOrganometallic CompoundsPancreatic NeoplasmsRadiometryRadiopharmaceuticalsSingle Photon Emission Computed Tomography Computed TomographyTerbiumTissue DistributionEdotreotideOctreotideOrganometallic CompoundsRadiopharmaceuticalsTerbium161TbAuger electronsDOTATOCfirst-in-humansSPECT/CT imaging

Identifiers

PMID33547209
PMCPMC8724898
OpenAlexW3127205125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.