Observational studyCardiovascular diabetology2021
Epicardial adipose tissue volume and coronary calcification among people living with diabetes: a cross-sectional study.
Observational study in Cardiovascular diabetology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 42 citations in OpenAlex.
- Diagnosis of coronary artery disease in patients with type 2 diabetes mellitus based on computed tomography and pericoronary adipose tissue radiomics: a retrospective cross-sectional study.Cardiovascular diabetology · 2023Trial
- Multimodality Non-Invasive Imaging Approach in Acute Coronary Syndrome: Diagnostic and Prognostic Assessment.Current cardiology reports · 2025Review
- Epicardial adipose tissue as an independent predictor of long-term outcome in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Epicardial adipose tissue volume and arterial stiffness in people living with diabetes: the METAB-CV-PWV study.Cardiovascular diabetology · 2025Article
- Ectopic adipose tissue in subsistence populations with minimal coronary disease, large left atria, and very low rates of atrial fibrillation.American journal of preventive cardiology · 2025Article
- Increased Amounts of Epicardial Fat Tissue Are Not Associated With Mitral Annular Calcification in Patients With Severe Aortic Stenosis Planned for Transcatheter Aortic Valve Implantation.Structural heart : the journal of the Heart Team · 2025Article
- Epicardial fat thickness predicts severe coronary artery disease and high mortality risk among ST-elevation myocardial infarction patients.Echo research and practice · 2025Article
- AI-Driven segmentation and morphogeometric profiling of epicardial adipose tissue in type 2 diabetes.Cardiovascular diabetology · 2025Article
- Detecting severe coronary artery stenosis in T2DM patients with NAFLD using cardiac fat radiomics-based machine learning.Scientific reports · 2025Article
- Imaging Inflammation: Epicardial Fat Density as an Imaging Marker of Cardiovascular Risk.Heart international · 2025Review
- Fully automated epicardial adipose tissue volume quantification with deep learning and relationship with CAC score and micro/macrovascular complications in people living with type 2 diabetes: the multicenter EPIDIAB study.Cardiovascular diabetology · 2024Article
- Epicardial adipose tissue defined by initial polytrauma CT of mechanically ventilated trauma patients: retrospective single-center cohort study to predict short-term outcomes.Emergency radiology · 2024Article
- Article
- [Arterial mediacalcinosis in patients with diabetes mellitus: etiopathogenetic and histopathological aspects].Problemy endokrinologii · 2024Review
- Analysis of Epicardial Adipose Tissue Texture in Relation to Coronary Artery Calcification in PCCT: The EAT Signature!Diagnostics (Basel, Switzerland) · 2024Article
- Epicardial and Pericoronary Adipose Tissue, Coronary Inflammation, and Acute Coronary Syndromes.Journal of clinical medicine · 2023Review
- Vascular calcification: from the perspective of crosstalk.Molecular biomedicine · 2023Review
- Visceral adipose tissue is an independent predictor and mediator of the progression of coronary calcification: a prospective sub-analysis of the GEA study.Cardiovascular diabetology · 2023Article
- The Importance of the Assessment of Epicardial Adipose Tissue in Scientific Research.Journal of clinical medicine · 2022Review
- The Role and Implications of Epicardial Fat in Coronary Atherosclerotic Disease.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpicardial adipose tissue (EAT) has anatomic and functional proximity to the heart and is considered a novel diagnostic marker and therapeutic target in cardiometabolic diseases. The aim of this study was to evaluate whether EAT volume was associated with coronary artery calcification (CAC) in people living with diabetes, independently of confounding factors.
methodsWe included all consecutive patients with diabetes whose EAT volume and CAC score were measured using computed tomography between January 1, 2019 and September 30, 2020 in the Department of Diabetology-Endocrinology-Nutrition at Avicenne Hospital, France. Determinants of EAT volume and a CAC score ≥ 100 Agatston units (AU) were evaluated.
resultsThe study population comprised 409 patients (218 men). Mean (± standard deviation) age was 57 ± 12 years, and 318, 56 and 35 had type 2 (T2D), type 1 (T1D), or another type of diabetes, respectively. Mean body mass index (BMI) was 29 ± 6 kg/m
conclusionsEAT volume was independently associated with CAC. As it may play a role in coronary atherosclerosis in patients with diabetes, reducing EAT volume through physical exercise, improved diet and pharmaceutical interventions may improve future cardiovascular risk outcomes in this population.
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