Evidence map›Paper›PMID 33546663›Full record

ArticleBMC complementary medicine and therapies2021

Evaluation of antioxidant and anticancer activity of crude extract and different fractions of Chlorella vulgaris axenic culture grown under various concentrations of copper ions.

Eman A El-Fayoumy, Sanaa M M Shanab, Hanan S Gaballa, Mohamed A Tantawy, Emad A Shalaby

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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  15. Exploring the antibacterial potential ofFrontiers in pharmacology · 2025
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  17. The Impact ofFoods (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eman A El-FayoumyDepartment of Botany and Microbiology, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Sanaa M M ShanabDepartment of Botany and Microbiology, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Hanan S GaballaDepartment of Biochemistry, Faculty of Agriculture, Cairo University, Giza, 12613, Egypt.
Mohamed A TantawyDepartment of Hormones. Medical Research Division, National Research Centre, Dokkie, Egypt.
Emad A ShalabyDepartment of Biochemistry, Faculty of Agriculture, Cairo University, Giza, 12613, Egypt. dremad2009@yahoo.com.ORCID http://orcid.org/0000-0003-2900-4833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChlorella vulgaris is a microalga potentially used for pharmaceutical, animal feed, food supplement, aquaculture and cosmetics. The current study aims to study the antioxidant and prooxidant effect of Chlorella vulgaris cultivated under various conc. of copper ions.

methodsThe axenic green microalgal culture of Chlorella vulgaris was subjected to copper stress conditions (0.00, 0.079, 0.158, 0.316 and 0.632 mg/L). The growth rate was measured at OD

resultsThe obtained results reported that nine out of these fractions exhibited more than 50% antioxidant activity and anticancer activity against Hela cancer cell lines. Based on IC

conclusionsThe authors recommend cultivation of Chlorella vulgaris in large scale under various stress conditions for use the crude extracts and semi purified fractions for making a pharmaco-economic value in Egypt and other countries.

Indexed as

Chlorella vulgarisAntineoplastic AgentsAntioxidantsBiphenyl CompoundsCell Culture TechniquesCell SurvivalCopperHeLa CellsHumansPicratesPlant Extracts1,1-diphenyl-2-picrylhydrazylAntineoplastic AgentsAntioxidantsBiphenyl CompoundsCopperPicratesPlant ExtractsActive ingredientsAntioxidant and anticancer activityChlorella vulgarisGrowth rate

Identifiers

PMID33546663
PMCPMC7863377

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.