Evidence map›Paper›PMID 33546628›Full record

ArticleBMC neurology2021

Abnormal regional homogeneity and its relationship with symptom severity in cervical dystonia: a rest state fMRI study.

Shubao Wei, Chunhui Lu, Xiuqiong Chen, Lu Yang, Jing Wei, Wenyan Jiang, Yang Liu, Hui Hui Li, Yuhong Qin, Yiwu Lei and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. SPECT Cerebral Perfusion Patterns in Isolated Cervical Dystonia.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Shubao WeiDepartment of Rehabilitation Medicine, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China.
Chunhui LuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Xiuqiong ChenDepartment of Rehabilitation Medicine, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China.
Lu YangDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Jing WeiDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Wenyan JiangDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yang LiuDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Hui Hui LiDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yuhong QinDepartment of Radiology, the First Affiliated Hospital, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Yiwu LeiDepartment of Radiology, the First Affiliated Hospital, Guangxi Medical University, Nanning, 530021, Guangxi, China.
Chao QinDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Caiyou HuDepartment of Rehabilitation Medicine, Jiangbin Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, Guangxi, China. cyhu.hua@163.com.
Shuguang LuoDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China. luoshuguang@stu.gxmu.edu.cn.ORCID http://orcid.org/0000-0002-4082-6136
Guangxi Medical University · CNRiverside Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

Guangxi Appropriate Technology for Medical and Health Research and Development Project S201415-05National Natural Science Foundation of China 81460203
6 · The paper itself

Abstract

backgroundAlthough several brain networks play important roles in cervical dystonia (CD) patients, regional homogeneity (ReHo) changes in CD patients have not been clarified. We investigated to explore ReHo in CD patients at rest and analyzed its correlations with symptom severity as measured by Tsui scale.

methodsA total of 19 CD patients and 21 gender-, age-, and education-matched healthy controls underwent fMRI scans at rest state. Data were analyzed by ReHo method.

resultsPatients showed increased ReHo in the right cerebellum crus I and decreased ReHo in the right superior medial prefrontal cortex (MPFC). Moreover, the right precentral gyrus, right insula, and bilateral middle cingulate gyrus also showed increased ReHo values. A significantly positive correlation was observed between ReHo value in the right cerebellum crus I and symptom severity (p < 0.05).

conclusionsOur investigation suggested abnormal ReHo existed in brain regions of the "pain matrix" and salience network (the right insula and bilateral middle cingulate gyrus), the motor network (the right precentral gyrus), the cerebellum and MPFC and further highlighted the significance of these networks in the pathology of CD.

Indexed as

AdultBrainBrain MappingFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedTorticollisCervical dystoniaDefault mode networkRegional homogeneityResting-state functional magnetic resonance

Identifiers

PMID33546628
PMCPMC7863325
OpenAlexW3112502476

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.