Evidence map›Paper›PMID 33546620›Full record

ArticleBMC geriatrics2021

Associations between post-stroke motor and cognitive function: a cross-sectional study.

Marte Stine Einstad, Ingvild Saltvedt, Stian Lydersen, Marie H Ursin, Ragnhild Munthe-Kaas, Hege Ihle-Hansen, Anne-Brita Knapskog, Torunn Askim, Mona K Beyer, Halvor Næss and 3 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 99 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 6 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02650531 completednot on this map

Norwegian COgnitive Impairment After STroke (NorCOAST) Study

TypeobservationalSponsorNorwegian University of Science and TechnologyRan2015 to 2018Enrolled816ConditionsDementia, Mild Cognitive Impairment, Stroke
NCT06500611 narecruitingnot on this mapstarted 2024, after this paper: background citation

Combined Effects Of Sensory Integration And Vestibular Exercises On Dizziness, Fall Risk And Quality Of Life In Post-Stroke Patients

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled38ConditionsPost StrokeArmsSensory Integration and Vestibular Exercise with Routine Physical Therapy, Vestibular Exercise with Routine Physical Therapy
3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 6 syntheses or guidelines pooled it, 181 citations in OpenAlex.

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  14. Lactate modulates microglial M2 polarizationJournal of translational internal medicine · 2026
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Marte Stine EinstadDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway. marte.s.einstad@ntnu.no.
Ingvild SaltvedtDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Stian LydersenDepartment of Mental Health, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Marie H UrsinDepartment of Medicine, Bærum Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Ragnhild Munthe-KaasDepartment of Medicine, Bærum Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Hege Ihle-HansenDepartment of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
Anne-Brita KnapskogDepartment of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.
Torunn AskimDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Mona K BeyerDepartment of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
Halvor NæssDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Yngve M SeljesethMedical Department, Ålesund Hospital, Møre and Romsdal Health Trust, Ålesund, Norway.
Hanne EllekjærDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Pernille ThingstadDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU-Norwegian University of Science and Technology, Trondheim, Norway.
Norwegian University of Science and Technology · NOOslo University Hospital · NOSt Olav's University Hospital · NOVestre Viken Hospital Trust · NOÅlesund Hospital · NOStavanger University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMotor and cognitive impairments are frequently observed following stroke, but are often managed as distinct entities, and there is little evidence regarding how they are related. The aim of this study was to describe the prevalence of concurrent motor and cognitive impairments 3 months after stroke and to examine how motor performance was associated with memory, executive function and global cognition.

methodsThe Norwegian Cognitive Impairment After Stroke (Nor-COAST) study is a prospective multicentre cohort study including patients hospitalized with acute stroke between May 2015 and March 2017. The National Institutes of Health Stroke Scale (NIHSS) was used to measure stroke severity at admission. Level of disability was assessed by the Modified Rankin Scale (mRS). Motor and cognitive functions were assessed 3 months post-stroke using the Montreal Cognitive Assessment (MoCA), Trail Making Test Part B (TMT-B), 10-Word List Recall (10WLR), Short Physical Performance Battery (SPPB), dual-task cost (DTC) and grip strength (Jamar®). Cut-offs were set according to current recommendations. Associations were examined using linear regression with cognitive tests as dependent variables and motor domains as covariates, adjusted for age, sex, education and stroke severity.

resultsOf 567 participants included, 242 (43%) were women, mean (SD) age was 72.2 (11.7) years, 416 (75%) had an NIHSS score ≤ 4 and 475 (84%) had an mRS score of ≤2. Prevalence of concurrent motor and cognitive impairment ranged from 9.5% for DTC and 10WLR to 22.9% for grip strength and TMT-B. SPPB was associated with MoCA (regression coefficient B = 0.465, 95%CI [0.352, 0.578]), TMT-B (B = -9.494, 95%CI [- 11.726, - 7.925]) and 10WLR (B = 0.132, 95%CI [0.054, 0.211]). Grip strength was associated with MoCA (B = 0.075, 95%CI [0.039, 0.112]), TMT-B (B = -1.972, 95%CI [- 2.672, - 1.272]) and 10WLR (B = 0.041, 95%CI [0.016, 0.066]). Higher DTC was associated with more time needed to complete TMT-B (B = 0.475, 95%CI [0.075, 0.875]) but not with MoCA or 10WLR.

conclusionThree months after suffering mainly minor strokes, 30-40% of participants had motor or cognitive impairments, while 20% had concurrent impairments. Motor performance was associated with memory, executive function and global cognition. The identification of concurrent impairments could be relevant for preventing functional decline.

trial registrationClinicalTrials.gov Identifier: NCT02650531 .

Indexed as

Cognitive DysfunctionStrokeAgedCognitionCohort StudiesCross-Sectional StudiesExecutive FunctionFemaleHumansMaleNeuropsychological TestsProspective StudiesCognitive functionFunctionMotor functionStroke

Identifiers

PMID33546620
PMCPMC7863272
OpenAlexW3111288252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.