Evidence map›Paper›PMID 33546585›Full record

ArticleBMC bioinformatics2021

GMO Genetic Elements Thesaurus (GMO-GET): a controlled vocabulary for the consensus designation of introduced or modified genetic elements in genetically modified organisms.

Paulien Adamse, Emilie Dagand, Karen Bohmert-Tatarev, Daniela Wahler, Manoela Miranda, Esther J Kok, Joachim Bendiek

Open access · goldAbstract read
In one paragraph

Article in BMC bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Paulien AdamseWageningen Food Safety Research (WFSR), PO Box 230, 6700 AE, Wageningen, Netherlands. paulien.adamse@wur.nl.ORCID http://orcid.org/0000-0002-7490-2424
Emilie DagandFederal Office of Consumer Protection and Food Safety, PO Box 11 02 60, 10832, Berlin, Germany.
Karen Bohmert-TatarevFederal Office of Consumer Protection and Food Safety, PO Box 11 02 60, 10832, Berlin, Germany.
Daniela WahlerFederal Office of Consumer Protection and Food Safety, PO Box 11 02 60, 10832, Berlin, Germany.
Manoela MirandaSecretariat of the Convention On Biological Diversity, 413 Saint-Jacques Street, Suite 800, Montreal, QC, H2Y 1N9, Canada.
Esther J KokWageningen Food Safety Research (WFSR), PO Box 230, 6700 AE, Wageningen, Netherlands.
Joachim BendiekFederal Office of Consumer Protection and Food Safety, PO Box 11 02 60, 10832, Berlin, Germany.
Federal Office of Consumer Protection and Food Safety · DEWageningen University & Research · NLBundesministerium für Landwirtschaft, Ernährung und Heimat · DESecretariat of the Pacific Regional Environment Programme · WS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious databases on genetically modified organisms (GMOs) exist, all with their specific focus to facilitate access to information needed for, e. g., the assistance in risk assessment, the development of detection and identification strategies or inspection and control activities. Each database has its unique approach towards the subject. Often these databases use different terminology to describe the GMOs. For adequate GMO addressing and identification and exchange of GMO-related information it is necessary to use commonly agreed upon concepts and terminology.

resultA hierarchically structured controlled vocabulary describing the genetic elements inserted into conventional GMOs, and GMOs developed by the use of gen(om)e-editing is presented: the GMO genetic element thesaurus (GMO-GET). GMO-GET can be used for GMO-related documentation, including GMO-related databases. It has initially been developed on the basis of two GMO databases, i.e. the Biosafety Clearing-House and the EUginius database.

conclusionThe use of GMO-GET will enable consistent and compatible information (harmonisation), also allowing an accurate exchange of information between the different data systems and thereby facilitating their interoperability. GMO-GET can also be used to describe genetic elements that are altered in organisms obtained through current targeted genome-editing techniques.

Indexed as

Gene EditingOrganisms, Genetically ModifiedPlants, Genetically ModifiedVocabulary, ControlledConsensusDatabases, FactualGenetic elementsGenome-editingGMOTargeted mutagenesisThesaurusVocabulary

Identifiers

PMID33546585
PMCPMC7863250
OpenAlexW3127220826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.