Evidence map›Paper›PMID 33546520›Full record

ReviewAnimals : an open access journal from MDPI2021

Impaired Reproductive Function in Equines: From Genetics to Genomics.

Nora Laseca, Gabriel Anaya, Zahira Peña, Yamila Pirosanto, Antonio Molina, Sebastián Demyda Peyrás

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Testicular Disorders in Equids: A Case Series.Animals : an open access journal from MDPI · 2026
    Article
  2. Review
  3. Rewilded horses in European nature conservation - a genetics, ethics, and welfare perspective.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Genotypic and Phenotypic Characterization ofAnimals : an open access journal from MDPI · 2023
    Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nora LasecaDepartamento de genética, Universidad de Córdoba, Campus de Rabanales Ctra, Madrid-Cádiz, km 396, 14071 Córdoba, Spain.ORCID 0000-0003-3753-6725
Gabriel AnayaDepartamento de genética, Universidad de Córdoba, Campus de Rabanales Ctra, Madrid-Cádiz, km 396, 14071 Córdoba, Spain.
Zahira PeñaDepartamento de genética, Universidad de Córdoba, Campus de Rabanales Ctra, Madrid-Cádiz, km 396, 14071 Córdoba, Spain.
Yamila PirosantoDepartamento de Producción Animal, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata 1900, Argentina.
Antonio MolinaDepartamento de genética, Universidad de Córdoba, Campus de Rabanales Ctra, Madrid-Cádiz, km 396, 14071 Córdoba, Spain.ORCID 0000-0002-9566-6600
Sebastián Demyda PeyrásDepartamento de Producción Animal, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata 1900, Argentina.ORCID 0000-0003-3286-2441
University of Córdoba · ESCentro Científico Tecnológico - La Plata · AR

Funding

Agencia Nacional de Promoción Científica y Tecnológica PICT2016-0359Agencia Nacional de Promoción Científica y Tecnológica PICT2018-0227Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL-2017-84217-PMinisterio de Economía, Industria y Competitividad, Gobierno de España PRE 2018-083492
6 · The paper itself

Abstract

Fertility is one of the key factors in the economic and productive success of the equine industry. Despite this, studies on the genetic causes affecting reproductive performance are scarce, especially in mares, where the genetic architecture of the reproductive traits is extremely complex. Today, with the increasing availability of new genomic methodologies for this species, we are presented with an interesting opportunity to understand the genetic basis of equine reproductive disorders. These include, among others, novel techniques for detecting chromosomal abnormalities, whose association with infertility in horses was established over 50 years ago; new sequencing technologies permitting an accurate detection of point mutations influencing fertility, as well as the study of inbreeding and molecular homozygosity, which has been widely suggested as one of the main causes of low reproductive performance in horses. Finally, over the last few years, reproductive performance has also been associated with copy number variants and candidate genes detected by genome-wide association studies on fertility traits. However, such studies are still scarce, probably because they depend on the existence of large and accurate phenotypic datasets of reproductive and/or fertility traits, which are still difficult to obtain in equines.

Indexed as

candidate genescopy number variationsfertilitygenome-wide association studiesgenomicsinbreedingmaresreproductive traitsstallions

Identifiers

PMID33546520
PMCPMC7913728
OpenAlexW3126541616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.