Evidence map›Paper›PMID 33546444›Full record

ArticleMicroorganisms2021

Evaluation of

João Heitor Colombelli Manfrão-Netto, Enzo Bento Queiroz, Kelly Assis Rodrigues, Cintia M Coelho, Hugo Costa Paes, Elibio Leopoldo Rech, Nádia Skorupa Parachin

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

João Heitor Colombelli Manfrão-NettoGrupo Engenharia de Biocatalisadores, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília 70910900, Brazil.ORCID 0000-0001-5600-0219
Enzo Bento QueirozGrupo Engenharia de Biocatalisadores, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília 70910900, Brazil.
Kelly Assis RodriguesGrupo Engenharia de Biocatalisadores, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília 70910900, Brazil.
Cintia M CoelhoDepartment of Genetics and Morphology, Institute of Biological Science, University of Brasília, Brasília 70910900, Brazil.ORCID 0000-0002-8564-3587
Hugo Costa PaesClinical Medicine Division, University of Brasília Medical School, University of Brasília, Brasília 70910900, Brazil.ORCID 0000-0002-1448-6852
Elibio Leopoldo RechBrazilian Agriculture Research Corporation-Embrapa-Genetic Resources and Biotechnology-CENARGEN, Brasília 70770917, Brazil.ORCID 0000-0001-8588-0673
Nádia Skorupa ParachinGrupo Engenharia de Biocatalisadores, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília 70910900, Brazil.ORCID 0000-0002-5392-4560
Universidade de Brasília · BRBrazilian Agricultural Research Corporation · BR

Funding

Fundação de Apoio à Pesquisa do Distrito Federal 0193.001605/2017.INCT Biologia Sintética (INCT-BioSyn) 465603/2014-9
6 · The paper itself

Abstract

Hyaluronic acid (HA) is a biopolymer formed by UDP-glucuronic acid and UDP-N-acetyl-glucosamine disaccharide units linked by β-1,4 and β-1,3 glycosidic bonds. It is widely employed in medical and cosmetic procedures. HA is synthesized by hyaluronan synthase (HAS), which catalyzes the precursors' ligation in the cytosol, elongates the polymer chain, and exports it to the extracellular space. Here, we engineer

Indexed as

genetic switch 5genomic editing 4hyaluronic acid 2methylotrophic yeast 3Ogataea polymorpha 1promoters 6

Identifiers

PMID33546444
PMCPMC7913781
OpenAlexW3127904674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.