Evidence map›Paper›PMID 33546442›Full record

ArticleJournal of clinical medicine2021

Safety and Effectiveness of Edoxaban in Atrial Fibrillation Patients in Routine Clinical Practice: One-Year Follow-Up from the Global Noninterventional ETNA-AF Program.

Raffaele De Caterina, Young-Hoon Kim, Yukihiro Koretsune, Chun-Chieh Wang, Takeshi Yamashita, Cathy Chen, Paul-Egbert Reimitz, Martin Unverdorben, Paulus Kirchhof

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  3. Sex differences in the initiation of antithrombotic therapy in patients with atrial fibrillation in Germany.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 7 countries.

Raffaele De CaterinaDivision of Cardiology, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, Pisa University Hospital and University of Pisa, Via Paradisa 2, 56124 Pisa, Italy.ORCID 0000-0003-1637-574X
Young-Hoon KimDivision of Cardiology, Korea University College of Medicine and Korea University Medical Center, 73 Goryeodae-ro Seongbuk-gu, Seoul 02841, Korea.
Yukihiro KoretsuneNational Hospital Organization Osaka National Hospital, Osaka 540-0006, Japan.
Chun-Chieh WangDivision of Cardiology, Department of Internal Medicine, Chang Gung University and Chang Gung Memrial Hospital, Taoyuan 33305, Taiwan.
Takeshi YamashitaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo 106-0031, Japan.ORCID 0000-0002-2544-8464
Cathy ChenDaiichi Sankyo, Inc., 211 Mount Airy Road, Basking Ridge, NJ 07920, USA.ORCID 0000-0003-1117-8085
Paul-Egbert ReimitzDaiichi Sankyo Europe, GmbH, Zielstattstraße 48, 81379 Munich, Germany.
Martin UnverdorbenDaiichi Sankyo, Inc., 211 Mount Airy Road, Basking Ridge, NJ 07920, USA.
Paulus KirchhofInstitute of Cardiovascular Sciences, University of Birmingham and SWBH and UHB NHS Trusts, IBR 136, Wolfson Drive, Birmingham B15 2TT, UK.
Daiichi Sankyo (United States) · USCardiovascular Institute Hospital · JPChang Gung University · TWDaiichi Sankyo (Germany) · DEGerman Centre for Cardiovascular Research · DEKorea University Medical Center · KROsaka National Hospital · JPUniversity of Pisa · IT

Funding

Daiichi-Sankyo N/A
6 · The paper itself

Abstract

Non-vitamin K antagonist oral anticoagulants such as edoxaban are the standard of care for stroke prevention in patients with atrial fibrillation (AF). The Global Edoxaban Treatment in routiNe clinical prActice (ETNA)-AF program integrates prospective, observational, noninterventional regional studies from Europe, Japan, and other Asian countries, collecting data on patient characteristics and clinical outcomes in unselected patients treated with edoxaban for stroke prevention in AF. Overall, 26,823 patients completed a 1-year follow-up and were treated with edoxaban; either 60 or 30 mg once daily. The majority (82.6%) of patients received the recommended doses according to the local label. At baseline, the median (interquartile range) age was 75 (68, 80) years, the CHA

Indexed as

anticoagulationatrial fibrillationdeathedoxabanmajor bleedingnon-vitamin K antagonist oral anticoagulant (NOAC)oral anticoagulantsstroke prevention

Identifiers

PMID33546442
PMCPMC7913627
OpenAlexW3127822960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.