Evidence map›Paper›PMID 33546415›Full record

ArticleInternational journal of environmental research and public health2021

A Positive Relationship between Exposure to Heavy Metals and Development of Chronic Diseases: A Case Study from Chile.

Sandra Cortés, Liliana Zúñiga-Venegas, Floria Pancetti, Alejandra Covarrubias, Muriel Ramírez-Santana, Héctor Adaros, Luis Muñoz

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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  11. Environmental Health Risk Perception: Adaptation of a Population-Based Questionnaire from Latin America.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sandra CortésDepartamento de Salud Pública, Escuela de Medicina, Universidad Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.ORCID 0000-0003-3293-1419
Liliana Zúñiga-VenegasLaboratorio de Investigaciones Biomédicas (LIB), Departamento de Preclínicas, Facultad de Medicina, Universidad Católica del Maule, Talca 3480005, Chile.
Floria PancettiLaboratorio de Neurotoxicología Ambiental, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Larrondo No. 1281, Coquimbo 1781421, Chile.
Alejandra CovarrubiasLaboratorio de Neurotoxicología Ambiental, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Larrondo No. 1281, Coquimbo 1781421, Chile.
Muriel Ramírez-SantanaDepartamento de Salud Pública, Facultad de Medicina, Universidad Católica del Norte, Coquimbo 1781421, Chile.ORCID 0000-0002-3642-6965
Héctor AdarosHospital Dr. Jerónimo Méndez, Chañaral, Chañaral 1490000, Chile.
Luis MuñozLaboratorio de Metrología Química, Comisión Chilena de Energía Nuclear, Santiago 7600713, Chile.
Universidad Católica del Norte · CLCatholic University of the Maule · CLComisión Chilena de Energía Nuclear · CLPontificia Universidad Católica de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chile is a mining country, where waste mining is frequently found in the vicinity of inhabited areas. To explore the association between metal exposure and alterations in glucose metabolism, inflammatory status, and oxidative stress in individuals with chronic exposure to metals, a cross-sectional study was performed with 25 volunteers, between 45-65 years old. Inductive coupled plasma mass spectrometry (ICP-MS) was used to measure urinary levels of total arsenic (As) and its metabolites, cooper, nickel, chromium, and lead. Lipid profile, glucose, and insulin were measured in blood, as well as inflammation (interleukin-6, IL-6) and oxidative stress (8-hydroxy-2'deoxyguanosine, 8-OHdG) markers. Increased levels of Low-density lipoprotein, high-density lipoproteins, cholesterol and 8-OHdG, and the index for homeostasis model assessment-insulin resistance (HOMA-IR) were observed in 72%, 60%, and 56% of the volunteers, respectively. Blood-glucose levels were correlated with dimethylarsinic acid (DMA) (R

Indexed as

Insulin ResistanceMetals, Heavy8-Hydroxy-2'-DeoxyguanosineAgedChileChronic DiseaseCross-Sectional StudiesHumansMiddle Aged8-Hydroxy-2'-DeoxyguanosineMetals, Heavycholesterolglycemiametabolic disordersmetal exposure

Identifiers

PMID33546415
PMCPMC7913508
OpenAlexW3129108076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.