Evidence map›Paper›PMID 33546366›Full record

ArticleInternational journal of molecular sciences2021

Design of PG-Surfactants Bearing Polyacrylamide Polymer Chain to Solubilize Membrane Proteins in a Surfactant-Free Buffer.

Taro Shimamoto, Tatsuki Nakakubo, Tomoyasu Noji, Shuhei Koeda, Keisuke Kawakami, Nobuo Kamiya, Toshihisa Mizuno

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Taro ShimamotoDepartment of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, Aichi 466-8555, Japan.
Tatsuki NakakuboDepartment of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, Aichi 466-8555, Japan.
Tomoyasu NojiResearch Center for Advanced Science & Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
Shuhei KoedaDepartment of Nanopharmaceutical Sciences, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho Showa-ku, Nagoya, Aichi 466-8555, Japan.
Keisuke KawakamiThe OCU Advanced Research Institute for Natural Science & Technology (OCARINA), Osaka City University, 3-3-138 Sugimoto-cho, Sumiyoshi, Osaka 558-8585, Japan.
Nobuo KamiyaThe OCU Advanced Research Institute for Natural Science & Technology (OCARINA), Osaka City University, 3-3-138 Sugimoto-cho, Sumiyoshi, Osaka 558-8585, Japan.
Toshihisa MizunoDepartment of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, Aichi 466-8555, Japan.ORCID 0000-0002-6878-5911
Nagoya Institute of Technology · JPOsaka City University · JPThe University of Tokyo · JP

Funding

Japan Society for the Promotion of Science 20K05705
6 · The paper itself

Abstract

The development of techniques capable of using membrane proteins in a surfactant-free aqueous buffer is an attractive research area, and it should be elucidated for various membrane protein studies. To this end, we examined a method using new solubilization surfactants that do not detach from membrane protein surfaces once bound. The designed solubilization surfactants, DKDKC

Indexed as

BuffersAcrylic ResinsChemical PhenomenaChemistry Techniques, SyntheticHydrogen-Ion ConcentrationMembrane ProteinsMolecular StructureParticle SizePolyacrylamidesPolymersSolubilitySurface-Active AgentsAcrylic ResinsBuffersMembrane ProteinsPolyacrylamidesPolymersSurface-Active Agentsmembrane proteinphotosystem Ipolyacrylamidesolubilization surfactantssurfactant-free

Identifiers

PMID33546366
PMCPMC7913505
OpenAlexW3129122548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.