Evidence map›Paper›PMID 33546249›Full record

ArticleCancers2021

Ritu Pandey, Nathan Johnson, Laurence Cooke, Benny Johnson, Yuliang Chen, Manjari Pandey, Jason Chandler, Daruka Mahadevan

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Melanoma in patients with Li-Fraumeni syndrome (Review).Experimental and therapeutic medicine · 2022
    Review
  14. Article
  15. Frontiers in oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ritu PandeyCancer Center, University of Arizona, Tucson, AZ 85724, USA.
Nathan JohnsonSchool of Medicine, Vanderbilt University, Nashville, TN 37325, USA.
Laurence CookeCancer Center, University of Arizona, Tucson, AZ 85724, USA.
Benny JohnsonMD Anderson Cancer Center, Houston, TX 77030, USA.
Yuliang ChenCancer Center, University of Arizona, Tucson, AZ 85724, USA.
Manjari PandeyWest Cancer Center, 7945 Wolf River Blvd, Germantown, TN 38138, USA.
Jason ChandlerWest Cancer Center, 7945 Wolf River Blvd, Germantown, TN 38138, USA.
Daruka MahadevanMays Cancer Center, University of Texas Health San Antonio, San Antonio, TX 78229, USA.
University of Arizona · USWest Cancer Center · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas MD Anderson Cancer Center · USVanderbilt University · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
6 · The paper itself

Abstract

Molecular profiling with next generation sequencing (NGS) delivers key information on mutant gene sequences, copy number alterations, gene-fusions, and with immunohistochemistry (IHC), is a valuable tool in clinical decision making for patients entering investigational agent trials. Our objective was to elucidate mutational profiles from primary versus metastatic sites from advanced cancer patients to guide rational therapy. All phase I patients (

Indexed as

FISHIHCNGSoncogenestargeted therapyTP53tumor suppressors

Identifiers

PMID33546249
PMCPMC7913278
OpenAlexW3127698360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.