Evidence map›Paper›PMID 33546195›Full record

ArticleNutrients2021

Shiori Akashi, Akihito Morita, Yusuke Mochizuki, Fuka Shibuya, Yasutomi Kamei, Shinji Miura

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shiori AkashiLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.ORCID 0000-0001-5096-6223
Akihito MoritaLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Yusuke MochizukiLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Fuka ShibuyaLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Yasutomi KameiLaboratory of Molecular Nutrition, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.
Shinji MiuraLaboratory of Nutritional Biochemistry, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.ORCID 0000-0001-8806-9763
University of Shizuoka · JPKyoto Prefectural University · JP

Funding

Council for Science, Technology and Innovation SIP14533567Ministry of Education, Culture, Sports, Science and Technology 26282184University of Shizuoka Grant for Scientific and Educational Research None
6 · The paper itself

Abstract

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is expressed in skeletal muscles and regulates systemic metabolism. Thus, nutraceuticals targeting skeletal muscle PGC-1α have attracted attention to modulate systemic metabolism. As auraptene contained in citrus fruits promotes lipid metabolism and improves mitochondrial respiration, it could increase mitochondrial function through PGC-1α. Therefore, we hypothesized that PGC-1α is activated by auraptene and investigated its effect using

Indexed as

AnimalsCell LineCitrusHEK293 CellsHumansMaleMiceMice, Inbred C57BLMitochondria, MuscleMuscle Fibers, Fast-TwitchMuscle, SkeletalMyoblastsOxidation-ReductionPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant ExtractsPowdersPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant ExtractsPowdersPpargc1a protein, mouse7-geranyloxycoumarinauraptenecitrus fruitfruitmitochondriamuscle fiberperoxisome proliferator-activated receptor-γ coactivator-1αskeletal muscle

Identifiers

PMID33546195
PMCPMC7913372
OpenAlexW3129045367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.