Evidence map›Paper›PMID 33546187›Full record

ArticleInternational journal of environmental research and public health2021

Combining Three Cohorts of World Trade Center Rescue/Recovery Workers for Assessing Cancer Incidence and Mortality.

Robert M Brackbill, Amy R Kahn, Jiehui Li, Rachel Zeig-Owens, David G Goldfarb, Molly Skerker, Mark R Farfel, James E Cone, Janette Yung, Deborah J Walker and 11 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Robert M BrackbillWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Amy R KahnBureau of Cancer Epidemiology, New York State Department of Health, Albany, NY 12237, USA.
Jiehui LiWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Rachel Zeig-OwensFire Department of the City of New York (FDNY), Brooklyn, NY 11201, USA.
David G GoldfarbFire Department of the City of New York (FDNY), Brooklyn, NY 11201, USA.
Molly SkerkerFire Department of the City of New York (FDNY), Brooklyn, NY 11201, USA.
Mark R FarfelWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
James E ConeWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Janette YungWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Deborah J WalkerWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Adrienne SolomonWorld Trade Center Health Registry, New York City Department of Health and Mental Hygiene, Long Island City, NY 11101, USA.
Baozhen QiaoBureau of Cancer Epidemiology, New York State Department of Health, Albany, NY 12237, USA.
Maria J SchymuraBureau of Cancer Epidemiology, New York State Department of Health, Albany, NY 12237, USA.ORCID 0000-0003-0587-8667
Christopher R DasaroDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Dana KristjanssonDepartment of Genetics and Bioinformatics, Norwegian Institute of Public Health, 0456 Oslo, Norway.
Mayris P WebberFire Department of the City of New York (FDNY), Brooklyn, NY 11201, USA.
Roberto G LucchiniDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Andrew C ToddDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
David J PrezantFire Department of the City of New York (FDNY), Brooklyn, NY 11201, USA.
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0002-3811-2791
Charles B HallDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-9982-8120

Funding

Extension of the World Trade Center RegistryU50OH009739 · OH · NEW YORK CITY HEALTH/MENTAL HYGIENE · PI FARFEL, MARK R · 2009 to 2025
$120.0M
WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
Mortality among WTC rescue and recovery workersU01OH011480 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOFFETTA, PAOLO, HALL, CHARLES B · 2017 to 2020
$2.4M
Incidence, Latency, and Survival of Cancer Following World Trade Center ExposureU01OH011315 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI BOFFETTA, PAOLO, HALL, CHARLES B · 2016 to 2018
$1.4M
Incidence, Latency, and Survival of Cancer Following World Trade Center ExposureU01OH011932 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HALL, CHARLES B · 2019 to 2019
$1.1M
Detection and Incidence of Thyroid Cancer among Three Cohorts of WTC-Exposed Rescue and Recovery WorkersU01OH011931 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ZEIG-OWENS, RACHEL · 2019 to 2019
$555k
Detection and Incidence of Thyroid Cancer among Three Cohorts of WTC-Exposed Rescue and Recovery WorkersU01OH011681 · OH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ZEIG-OWENS, RACHEL · 2018 to 2018
$350k
NCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032INCI NIH HHS P30 CA013330NIOSH CDC HHS U01OH011315NIOSH CDC HHS U01 OH011480NIOSH CDC HHS U01 OH011681NIOSH CDC HHS U01 OH011931NIOSH CDC HHS U01 OH011932NIOSH CDC HHS U50 OH009739
6 · The paper itself

Abstract

Three cohorts including the Fire Department of the City of New York (FDNY), the World Trade Center Health Registry (WTCHR), and the General Responder Cohort (GRC), each funded by the World Trade Center Health Program have reported associations between WTC-exposures and cancer. Results have generally been consistent with effect estimates for excess incidence for all cancers ranging from 6 to 14% above background rates. Pooling would increase sample size and de-duplicate cases between the cohorts. However, pooling required time consuming steps: obtaining Institutional Review Board (IRB) approvals and legal agreements from entities involved; establishing an honest broker for managing the data; de-duplicating the pooled cohort files; applying to State Cancer Registries (SCRs) for matched cancer cases; and finalizing analysis data files. Obtaining SCR data use agreements ranged from 6.5 to 114.5 weeks with six states requiring >20 weeks. Records from FDNY (

Indexed as

NeoplasmsOccupational ExposureSeptember 11 Terrorist AttacksHumansIncidenceNew YorkNew York CityRescue Workcancerexposurepooling cohortsrescue and recovery workersWorld Trade Center

Identifiers

PMID33546187
PMCPMC7913216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.