Evidence map›Paper›PMID 33546176›Full record

ArticleMaterials (Basel, Switzerland)2021

Whither Magnetic Hyperthermia? A Tentative Roadmap.

Irene Rubia-Rodríguez, Antonio Santana-Otero, Simo Spassov, Etelka Tombácz, Christer Johansson, Patricia De La Presa, Francisco J Teran, María Del Puerto Morales, Sabino Veintemillas-Verdaguer, Nguyen T K Thanh and 17 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Advances in magnetic induction hyperthermia.Frontiers in bioengineering and biotechnology · 2024
    Review
  15. On the Evaluation of the Hyperthermic Efficiency of Magnetic Scaffolds.IEEE open journal of engineering in medicine and biology · 2024
    Article
  16. Article
  17. Article
  18. Magneto-Responsive Textiles for Non-Invasive Heating.International journal of molecular sciences · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Irene Rubia-RodríguezIMDEA Nanoscience, Faraday 9, 28049 Madrid, Spain.
Antonio Santana-OteroIMDEA Nanoscience, Faraday 9, 28049 Madrid, Spain.
Simo SpassovGeophysical Centre of the Royal Meteorological Institute, 1 rue du Centre Physique, 5670 Dourbes, Belgium.
Etelka TombáczSoós Water Technology Research and Development Center, University of Pannonia, 8200 Nagykanizsa, Hungary.
Christer JohanssonRISE Research Institutes of Sweden, Sensors and Materials, Arvid Hedvalls Backe 4, 411 33 Göteborg, Sweden.ORCID 0000-0002-6662-8023
Patricia De La PresaInstituto de Magnetismo Aplicado UCM-ADIF-CSIC, A6 22,500 km, 29260 Las Rozas, Spain.ORCID 0000-0002-9456-8320
Francisco J TeranIMDEA Nanoscience, Faraday 9, 28049 Madrid, Spain.
María Del Puerto MoralesDepartment of Energy, Environment and Health, Instituto de Ciencia de Materiales de Madrid (ICMM/CSIC), Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain.
Sabino Veintemillas-VerdaguerDepartment of Energy, Environment and Health, Instituto de Ciencia de Materiales de Madrid (ICMM/CSIC), Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain.ORCID 0000-0002-3015-1470
Nguyen T K ThanhUCL Healthcare Biomagnetics and Nanomaterials Laboratories, 21 Albemarle Street, London W1S 4BS, UK.ORCID 0000-0002-4131-5952
Maximilian O BesenhardDepartment of Chemical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.ORCID 0000-0002-5079-617X
Claire WilhelmLaboratoire Matière et Systèmes Complexes MSC, Université de Paris/CNRS, 75013 Paris, France.
Florence GazeauLaboratoire Matière et Systèmes Complexes MSC, Université de Paris/CNRS, 75013 Paris, France.
Quentin HarmerEndomag, The Jeffreys Building, St John's Innovation Park, Cowley Road, Cambridge CB4 0WS, UK.
Eric MayesEndomag, The Jeffreys Building, St John's Innovation Park, Cowley Road, Cambridge CB4 0WS, UK.
Bella B ManshianTranslational Cell and Tissue Research Unit, Department of Imaging and Pathology, Biomedical Sciences Group, B-3000 Leuven, Belgium.
Stefaan J SoenenTranslational Cell and Tissue Research Unit, Department of Imaging and Pathology, Biomedical Sciences Group, B-3000 Leuven, Belgium.
Yuanyu GuINMA Instituto de Nanociencia de Materiales de Aragón, Pedro Cerbuna 12, 50009 Zaragoza, Spain.
Ángel MillánINMA Instituto de Nanociencia de Materiales de Aragón, Pedro Cerbuna 12, 50009 Zaragoza, Spain.ORCID 0000-0003-0828-3212
Eleni K EfthimiadouChemistry Department, Inorganic Chemistry Laboratory, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.
Jeff GaudetMagnetic Insight, Alameda, CA 94501, USA.
Patrick GoodwillMagnetic Insight, Alameda, CA 94501, USA.
James MansfieldMagnetic Insight, Alameda, CA 94501, USA.
Uwe SteinhoffPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587 Berlin, Germany.ORCID 0000-0001-9138-8327
James WellsPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587 Berlin, Germany.
Frank WiekhorstPhysikalisch-Technische Bundesanstalt, Abbestraße 2-12, 10587 Berlin, Germany.ORCID 0000-0003-0608-1473
Daniel OrtegaIMDEA Nanoscience, Faraday 9, 28049 Madrid, Spain.ORCID 0000-0002-7441-8640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.

Indexed as

cancerhysteresis lossesmagnetic hyperthermiamagnetic nanoparticlesmagnetic particle imagingnanoparticles synthesisnanotoxicitystandardizationtheranosticsthermometry

Identifiers

PMID33546176
PMCPMC7913249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.