Evidence map›Paper›PMID 33545964›Full record

ArticleMedicine2021

Evaluation on blood coagulation and C-reactive protein level among children with mycoplasma pneumoniae pneumonia by different chest imaging findings.

Juan Wang, Jianping Mao, Gang Chen, Yuanmei Huang, Jinjin Zhou, Changlong Gao, Danting Jin, Chenying Zhang, Juan Wen, Jun Sun

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  10. Biomarkers associated with the diagnosis and prognosis ofFrontiers in cellular and infection microbiology · 2025
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  13. [Value of calprotectin S100 A8/A9 in predicting the severity ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  14. Clinical characteristics and risk factors forFrontiers in pediatrics · 2024
    Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Juan WangDepartment of Pediatrics.
Jianping MaoDepartment of Hematology.
Gang ChenDepartment of Pediatrics.
Yuanmei HuangDepartment of Pediatrics.
Jinjin ZhouDepartment of Pediatrics.
Changlong GaoDepartment of Pediatrics.
Danting JinDepartment of Medical Laboratory.
Chenying ZhangDepartment of Respiratory, the First People's Hospital of Lianyungang, Lianyungang, China.
Juan WenNanjing Maternity and Child Health Care Institute, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.
Jun SunDepartment of Pediatrics.
Nanjing Maternity and Child Health Care Hospital · CNThe First People’s Hospital of Lianyungang · CN

Funding

the Foundation of the First people's Hospital of Lianyungang QN150303
6 · The paper itself

Abstract

abstractMycoplasma pneumoniae infection may induce a systemic hypercoagulable abnormality, like organ embolism and infarction. Indexes of blood coagulation and C-reactive protein (CRP) have been reported different between healthy people and mycoplasma pneumoniae pneumonia (MPP) patients, but this difference in MPP patients with different chest imaging findings has rarely been reported.We performed a retrospective study of 101 children with MPP and 119 controls, combined with radiological examination and blood tests, to compare the blood coagulation and CRP level among MPP children with different chest imaging findings.For the MPP children with different chest imaging findings, there were significant differences in CRP, fibrinogen (FIB) and D-dimer (D-D) levels among subgroups (P = .004, P = .008 and P < .001 respectively). The CRP level in group of interstitial pneumonia was significantly higher than that in groups of bronchopneumonia and hilar shadow thickening (P = .003 and P = .001 respectively). And the FIB and D-D values in group of lung consolidation were significantly higher than that in the other 3 groups (all P < .05). When compared with controls, the white blood cell, CRP, FIB, and D-D levels in MPP children were significantly higher, and the activated partial thromboplastin time and thrombin time levels were significantly lower (all P < .05).Our results showed that CRP level changed most significantly in group of interstitial pneumonia, whereas FIB, D-D levels changed most significantly in the lung consolidation group.

Indexed as

AdolescentBlood Coagulation FactorsChildChild, PreschoolC-Reactive ProteinFemaleFibrin Fibrinogen Degradation ProductsFibrinogenHumansInfantMaleMycoplasma pneumoniaePneumonia, MycoplasmaThoraxBlood Coagulation FactorsC-Reactive ProteinFibrin Fibrinogen Degradation Productsfibrin fragment DFibrinogen

Identifiers

PMID33545964
PMCPMC7837868
OpenAlexW3122804359

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.