Evidence map›Paper›PMID 33545021›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.

Annette T Hastie, David T Mauger, Loren C Denlinger, Andrea Coverstone, Mario Castro, Serpil Erzurum, Nizar Jarjour, Bruce D Levy, Deborah A Meyers, Wendy C Moore and 5 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 59 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Novel Machine Learning Identifies 5 Asthma Phenotypes Using Cluster Analysis of Real-World Data.The journal of allergy and clinical immunology. In practice · 2024
    Article
  17. Sputum microbiota and inflammatory subtypes in asthma, COPD, and its overlap.The journal of allergy and clinical immunology. Global · 2024
    Article
  18. Article
  19. Role and regulators of NFrontiers in pharmacology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Annette T HastieSchool of Medicine, Wake Forest University, Winston-Salem, North Carolina.ORCID 0000-0001-6607-7797
David T MaugerPenn State College of Medicine, Penn State University, Hershey, Pennsylvania.
Loren C DenlingerUniversity of Wisconsin-Madison, Madison, Wisconsin.
Andrea CoverstoneSchool of Medicine, Washington University, St. Louis, Missouri.
Mario CastroSchool of Medicine, Washington University, St. Louis, Missouri.
Serpil ErzurumCleveland Clinic, Cleveland, Ohio.
Nizar JarjourUniversity of Wisconsin-Madison, Madison, Wisconsin.
Bruce D LevyBrigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-9515-5731
Deborah A MeyersCollege of Medicine, University of Arizona, Tucson, Arizona.
Wendy C MooreSchool of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Brenda R PhillipsPenn State College of Medicine, Penn State University, Hershey, Pennsylvania.
Sally E WenzelUniversity of Pittsburgh, Pittsburgh, Pennsylvania; and.
John V FahyUniversity of California-San Francisco, San Francisco, California.
Elliot IsraelBrigham and Women's Hospital, Boston, Massachusetts.
Eugene R BleeckerCollege of Medicine, University of Arizona, Tucson, Arizona.
Brigham and Women's Hospital · USPennsylvania State University · USUniversity of Arizona · USUniversity of Wisconsin–Madison · USWake Forest University · USWashington University in St. Louis · USCleveland Clinic · USUniversity of California, San Francisco · USUniversity of Pittsburgh · US

Funding

RADx-UP: Improving the Response of Local Urban and Rural Communities to Disparities in Covid-19 TestingUL1TR002366 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mario Castro, JAMES STEVEN LEEDER · 2017 to 2026
$44.3M
Rapid saliva antigen test for SARS-CoV-2 detectionU01HL146002 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ARONICA, MARK A, CASTRO, MARIO · 2019 to 2023
$17.3M
Clinical Coordinating Center for the Severe Asthma Research Program (SARP)U10HL109086 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2011 to 2017
$8.1M
AMSA: ALXR/FBR Mediated Signaling in Severe AsthmaU10HL109172 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, LEVY, BRUCE D · 2011 to 2016
$4.2M
Airway redox biochemistry as a deteriminant of asthma phenotype during adolescen*U10HL109250 · NHLBI · UNIVERSITY OF VIRGINIA · PI ERZURUM, SERPIL C., GASTON, BENJAMIN · 2011 to 2016
$4.2M
Clinical and Molecular Phenotypes of Severe AsthmaU10HL109146 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FAHY, JOHN V · 2011 to 2016
$4.0M
Implications and Stability of Clinical and Molecular Phenotypes of Severe AsthmaU10HL109152 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WENZEL, SALLY E · 2011 to 2016
$3.9M
Stability of Severe Asthma Phenotypes: Impact of ExacerbationsU10HL109168 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JARJOUR, NIZAR N · 2011 to 2016
$3.9M
Severe Asthma Research Program (SARP)-Washington UniversityU10HL109257 · NHLBI · WASHINGTON UNIVERSITY · PI CASTRO, MARIO · 2011 to 2016
$3.8M
Longitudinal Phenomics and Genetics of Severe AsthmaU10HL109164 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLEECKER, EUGENE ROLAND, MEYERS, DEBORAH A. · 2011 to 2016
$3.8M
NCATS NIH HHS UL1 TR002366NHLBI NIH HHS U01 HL146002NHLBI NIH HHS U10 HL109086NHLBI NIH HHS U10 HL109146NHLBI NIH HHS U10 HL109152NHLBI NIH HHS U10 HL109164NHLBI NIH HHS U10 HL109168NHLBI NIH HHS U10 HL109172NHLBI NIH HHS U10 HL109250NHLBI NIH HHS U10 HL109257
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAsthmaCohort StudiesEosinophilsFemaleGenetic VariationGranulocytesHumansInflammationLungMaleMiddle AgedPhenotypeRespiratory Function Testseosinophilsexacerbationshealthcare uselongitudinal inflammationneutrophils

Identifiers

PMID33545021
PMCPMC8017570
OpenAlexW3126557152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.