ArticlePloS one2021
COVID-19 associated anxiety enhances tinnitus.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- The Effects of COVID-19 on Tinnitus Severity and Quality of Life in Individuals With Subjective Tinnitus.Brain and behavior · 2025Article
- A Scoping Review of Corticosterone-Induced Changes in Ionotropic Glutamate Receptor Levels and Localization in the Rodent Brain: Implications for the Auditory System.Brain sciences · 2025Review
- Prevalence and prognosis of tinnitus in post-COVID-19 patients: a cross-sectional survey.Epidemiology and infection · 2024Article
- Tinnitus and COVID-19: effect of infection, vaccination, and the pandemic.Frontiers in public health · 2024Article
- [Research advances in the correlation between chronic subjective tinnitus and anxiety state].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Review
- An online survey on clinical characteristics of otologic symptoms linked to COVID-19 infection.Frontiers in public health · 2023Article
- Comparative Study of Audiovestibular Symptoms between Early and Late Variants of COVID-19.Audiology research · 2022Article
- Audio-Vestibular Profile of COVID-19; Systematic Review and Meta-analysis.Iranian journal of otorhinolaryngology · 2022Article
- Impact of the COVID-19 Lockdown on Patients with Chronic Tinnitus-Preliminary Results.Audiology research · 2022Article
- Effects of the coronavirus disease 2019 pandemic on subjective tinnitus perception.The Journal of laryngology and otology · 2022Article
- The Impact of COVID-19 Confinement on Tinnitus and Hearing Loss in Older Adults: Data From the LOST in Lombardia Study.Frontiers in neurology · 2022Article
- Trajectory of COVID-related tinnitus over the pandemic timeline.Brazilian journal of otorhinolaryngologyArticle
- New onset tinnitus in the absence of hearing changes following COVID-19 infection.American journal of otolaryngologyArticle
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate if the anxiety associated with coronavirus disease 2019 (COVID-19) is a promoting factor to tinnitus. A retrospective research design collected from 188 tinnitus patients, was used to compare the clinical characteristics of tinnitus between the patients in 2020 under pandemic pressure and those from the matching period in 2019. While anxiety was quantified using the Zung's Self-rating Anxiety Scale (SAS), tinnitus severity was evaluated using the Tinnitus Handicap Inventory (THI) questionnaire and the test of tinnitus loudness (TL). The assessments were repeated after the sound therapy plus educational counselling (STEC) for 38 patients in 2020 and 58 patients in 2019 and compared with EC alone therapy for 42 patients in 2020 and 17 patients in 2019. A large increase in anxiety was evident in 2020 in both case rate and SAS. The treatment of both methods was less effective in 2020. SAS, THI and TL were all deteriorated after the EC alone treatment in 2020, while an improvement was seen in 2019. This suggests that EC alone could not counteract the stress by COVID-19 at all, and the stress, if not managed well, can significantly increase the severity of tinnitus and associated anxiety. By using the EC subgroup in virtual control, we conclude that anxiety can serve as a promoting factor to tinnitus. We believe that this is the first study report that confirm the causative/promotive role of anxiety on tinnitus during COVID-19 pandemic.
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