Evidence map›Paper›PMID 33544656›Full record

ArticleAmerican journal of respiratory cell and molecular biology2021

IFN Stimulates ACE2 Expression in Pediatric Airway Epithelial Cells.

Kyle Salka, Karima Abutaleb, Elizabeth Chorvinsky, Girija Thiruvengadam, Maria Arroyo, Jose L Gomez, Maria J Gutierrez, Dinesh K Pillai, Jyoti K Jaiswal, Gustavo Nino

Open access · greenAbstract readLetter
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
  8. Exposing the Two Contrasting Faces of STAT2 in Inflammation.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Review
  9. Understanding on the possible routes for SARS CoV-2 invasion via ACE2 in the host linked with multiple organs damage.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
    Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kyle SalkaChildren's National Hospital Washington, DC.
Karima AbutalebChildren's National Hospital Washington, DC.
Elizabeth ChorvinskyChildren's National Hospital Washington, DC.
Girija ThiruvengadamChildren's National Hospital Washington, DC.
Maria ArroyoChildren's National Hospital Washington, DC.
Jose L GomezYale University School of Medicine New Haven, Connecticut and.
Maria J GutierrezJohns Hopkins University Baltimore, Maryland.
Dinesh K PillaiChildren's National Hospital Washington, DC.
Jyoti K JaiswalChildren's National Hospital Washington, DC.
Gustavo NinoChildren's National Hospital Washington, DC.
Children's National · USJohns Hopkins University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
Systems Biology of a MicroRNA Network in Neutrophilic AsthmaR01HL153604 · NHLBI · YALE UNIVERSITY · PI GOMEZ-VILLALOBOS, JOSE LUIS · 2020 to 2024
$3.4M
THE HUMAN INFANT AIRWAY EPITHELIUM AND RECURRENT WHEEZING AFTER RV AND RSV INFECTIONR01HL141237 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2019 to 2022
$2.8M
Imaging biomarkers of severe respiratory infections in premature infants Phase IIR42HL145669 · NHLBI · KITWARE, INC. · PI ENQUOBAHRIE, ANDINET ASMAMAW, LINGURARU, MARIUS GEORGE · 2021 to 2022
$1.7M
Exosomal miR-155 regulates airway epithelial immune responses in infants with rhinovirus infectionR21AI130502 · NIAID · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2017 to 2018
$495k
TSLP responses in the human infant airway epithelium and recurrent wheezing after RV and RSV InfectionR56HL141237 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI NINO, GUSTAVO · 2018 to 2018
$442k
Imaging Biomarkers of Severe Respiratory Infections in Premature InfantsR41HL145669 · NHLBI · KITWARE, INC. · PI ENQUOBAHRIE, ANDINET ASMAMAW, LINGURARU, MARIUS GEORGE · 2018 to 2018
$225k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL141237NHLBI NIH HHS R01 HL153604NHLBI NIH HHS R41 HL145669NHLBI NIH HHS R42 HL145669NHLBI NIH HHS R56 HL141237NIAID NIH HHS R21 AI130502NICHD NIH HHS U54 HD090257
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin-Converting Enzyme 2Cells, CulturedEnzyme InductionEpithelial CellsFemaleHumansInfantInterferon-gammaMaleNasal MucosaPoly I-CACE2 protein, humanAngiotensin-Converting Enzyme 2Interferon-gammaPoly I-C

Identifiers

PMID33544656
PMCPMC8008803
OpenAlexW3126431032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.