Evidence map›Paper›PMID 33544446›Full record

ArticleHuman brain mapping2021

Resting cerebral oxygen metabolism exhibits archetypal network features.

Nicholas A Hubbard, Monroe P Turner, Kevin R Sitek, Kathryn L West, Jakub R Kaczmarzyk, Lyndahl Himes, Binu P Thomas, Hanzhang Lu, Bart Rypma

Abstract read
In one paragraph

Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicholas A HubbardMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID 0000-0002-8209-4295
Monroe P TurnerSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA.
Kevin R SitekMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Kathryn L WestSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA.
Jakub R KaczmarzykMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Lyndahl HimesSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA.
Binu P ThomasSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA.
Hanzhang LuDepartment of Radiology, John's Hopkins University School of Medicine, Baltimore, Maryland, USA.
Bart RypmaSchool of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas, USA.

Funding

Testing the Efficacy of Ibudilast to Attenuate Meth-seeking and Associated Synaptic Inflammation at the Synapse (TEAMS)P20GM130461 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI Tierney Kyle Ahrold Lorenz · 2019 to 2026
$20.6M
BOLD and its discontents: age-differences in the neurophysiology of fMRI signalR01AG047972 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG, RYPMA, BART · 2015 to 2019
$1.7M
Physiological, neural and cognitive bases of age-related working memory changeR01AG029523 · NIA · UNIVERSITY OF TEXAS DALLAS · PI RYPMA, BART · 2007 to 2010
$1.2M
Adolescent Brain Bases of Intergenerational Risk for DepressionF32MH114525 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HUBBARD, NICHOLAS · 2017 to 2019
$123k
Subcortical auditory feedback mechanisms in speech: Function and structureF31DC015695 · NIDCD · HARVARD MEDICAL SCHOOL · PI SITEK, KEVIN RICHARD · 2016 to 2017
$68k
NIA NIH HHS R01 AG029523NIA NIH HHS R01 AG047972NIDCD NIH HHS F31 DC015695NIGMS NIH HHS P20 GM130461NIMH NIH HHS F32 MH114525
6 · The paper itself

Abstract

Standard magnetic resonance imaging approaches offer high-resolution but indirect measures of neural activity, limiting understanding of the physiological processes associated with imaging findings. Here, we used calibrated functional magnetic resonance imaging during the resting state to recover low-frequency fluctuations of the cerebral metabolic rate of oxygen (CMRO

Indexed as

ConnectomeAdultBrainCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingMaleNerve NetOxygenYoung AdultOxygenfMRIfunctional connectivityoxygen metabolismresting state

Identifiers

PMID33544446
PMCPMC8046048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.