Evidence map›Paper›PMID 33544363›Full record

ReviewApplied biochemistry and biotechnology2021

Cold Active Lipases: Biocatalytic Tools for Greener Technology.

Nutan Mhetras, Vidhyashri Mapare, Digambar Gokhale

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cold-Active Lipase from the Ice CaveMolecules (Basel, Switzerland) · 2024
    Article
  10. Production, purification, and characterization of cold-active lipase from the psychrotroph Pseudomonas sp. A6.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Industrial Biotechnology Based on Enzymes From Extreme Environments.Frontiers in bioengineering and biotechnology · 2022
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nutan MhetrasSymbiosis School of Biological Sciences, Symbiosis International (Deemed University) Lavale, Pune, India.ORCID https://orcid.org/0000-0001-8257-0549
Vidhyashri MapareNCIM Resource Center, CSIR-National Chemical Laboratory, Pune, 411008, India.ORCID https://orcid.org/0000-0002-8973-6131
Digambar GokhaleNCIM Resource Center, CSIR-National Chemical Laboratory, Pune, 411008, India. dv.gokhale@ncl.res.in.ORCID http://orcid.org/0000-0002-2895-2869
National Chemical Laboratory · INSymbiosis International University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipases are enzymes that catalyze the ester bond hydrolysis in triglycerides with the release of fatty acids, mono- and diglycerides, and glycerol. The microbial lipases account for $400 million market size in 2017 and it is expected to reach $590 million by 2023. Many biotechnological processes are expedited at high temperatures and hence much research is dealt with thermostable enzymes. Cold active lipases are now gaining importance in the detergent, synthesis of chiral intermediates and frail/fragile compounds, and food and pharmaceutical industries. In addition, they consume less energy since they are active at low temperatures. These cold active lipases have not been commercially exploited so far compared to mesophilic and thermophilc lipases. Cold active lipases are distributed in microbes found at low temperatures. Only a few microbes were studied for the production of these enzymes. These cold-adapted enzymes show increased flexibility of their structures in response to freezing effect of the cold habitats. This review presents an update on cold-active lipases from microbial sources along with some structural features justifying high enzyme activity at low temperature. In addition, recent achievements on their use in various industries will also be discussed.

Indexed as

BiocatalysisCold TemperatureGreen Chemistry TechnologyLipaseLipaseCold active lipasesFrail compoundsPsychrophilic microbesSynthesis of chiral molecules

Identifiers

PMID33544363
OpenAlexW3128426793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.