Evidence map›Paper›PMID 33544362›Full record

ArticleProbiotics and antimicrobial proteins2021

Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress.

Mehulkumar Ramanlal Chorawala, Sweta Chauhan, Rakesh Patel, Gaurang Shah

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

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  15. Frontiers in immunology · 2024
    Article
  16. Recent Perspective ofAntioxidants (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Oligosaccharides isolated fromFrontiers in nutrition · 2023
    Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mehulkumar Ramanlal ChorawalaDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India. mehul.chorawala@lmcp.ac.in.ORCID http://orcid.org/0000-0002-3724-0986
Sweta ChauhanDepartment of Pharmacology, K. B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat, India.
Rakesh PatelDepartment of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA.
Gaurang ShahDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
B.J. Medical College · INUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there are no effective therapeutic agents to limit intestinal mucosal damage associated with inflammatory bowel disease (IBD). Based on several clinical studies, probiotics have emerged as a possible novel therapeutic strategy for IBD; however, their possible mechanisms are still poorly understood. Although probiotics in murine and human improve disease severity, very little is known about the specific contribution of cell wall contents of probiotics in IBD. Herein, we investigated the protective effects of cell wall contents of three Lactobacillus species in lipopolysaccharide (LPS)-induced colitis rats. LPS-sensitized rats were rendered colitic by colonic instillation of LPS (500 µg/rat) for 14 consecutive days. Concurrently, cell wall contents isolated from 10

Indexed as

ColitisLactobacillusOxidative StressProbioticsAnimalsCell WallLipopolysaccharidesRatsWeight LossLipopolysaccharidesIBDImmuno-inflammationLactobacillus speciesLipopolysaccharideOxidative stressProbiotics

Identifiers

PMID33544362
OpenAlexW3129041840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.