Evidence map›Paper›PMID 33544347›Full record

ArticleEnvironmental science and pollution research international2021

Individual exposure to urban air pollution and its correlation with placental angiogenic markers in the first trimester of pregnancy, in São Paulo, Brazil.

Karen Hettfleisch, Mariana Azevedo Carvalho, Mara Sandra Hoshida, Luciana Duzolina Manfré Pastro, Silvia Regina Dias Medici Saldiva, Sandra Elisabete Vieira, Rossana Pulcineli Vieira Francisco, Paulo Hilário Nascimento Saldiva, Lisandra Stein Bernardes

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karen HettfleischDisciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Mariana Azevedo CarvalhoDivisao de Clinica Obstetrica, Hospital das Clinicas HCFMUSP, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Mara Sandra HoshidaLIM 57 Laboratorio de Fisiologia Obstetrica, Hospital das Clinicas HCFMUSP, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil.
Luciana Duzolina Manfré PastroDisciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Silvia Regina Dias Medici SaldivaInstituto de Saude da Secretaria do Estado da Saude/SES-SP, São Paulo, Brazil.
Sandra Elisabete VieiraDepartamento de Pediatria, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil.
Rossana Pulcineli Vieira FranciscoDisciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Paulo Hilário Nascimento SaldivaDepartamento de Patologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Lisandra Stein BernardesDisciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil. lisbernardes@usp.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 2009/17315-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2008/57717-6
6 · The paper itself

Abstract

Pollution of the atmosphere is known that may lead to adverse obstetric outcomes, including fetal growth restriction, gestational hypertension, and preeclampsia. Such disorders are correlated with imbalances in angiogenic factors, which may also be involved in the pathological mechanism as the pollutants impact placental and maternal physiology. In the first trimester of gestation, this study assessed the outcomes of personal maternal short period exposure to air pollution on soluble fms-like tyrosine kinase 1 (sFlt1) and placental growth factor (PLGF) of pregnant women blood concentrations. This was a cross-sectional study, held in the city of São Paulo, Brazil, and conducted with low-risk pregnant women, who carried personal passive nitrogen dioxide (NO

Indexed as

Air PollutionVascular Endothelial Growth Factor Receptor-1BiomarkersBrazilCross-Sectional StudiesFemaleHumansPlacentaPlacenta Growth FactorPregnancyPregnancy Trimester, FirstBiomarkersFLT1 protein, humanPlacenta Growth FactorVascular Endothelial Growth Factor Receptor-1Air pollutionAngiogenic factorsFirst trimesterPlacental growth factor (PLGF)PregnancySoluble fms-like tyrosine kinase 1 (sFlt1)

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.