Evidence map›Paper›PMID 33544301›Full record

ArticleFolia microbiologica2021

Isolation of endophytic fungi with antimicrobial activity from medicinal plant Zanthoxylum simulans Hance.

Jimmy Kuo, Chin-Feng Chang, Wei-Chiung Chi

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In one paragraph

Article in Folia microbiologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. EndophyticFrontiers in microbiology · 2025
    Article
  4. Article
  5. Diversity of Endophytes ofLife (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Characterization of aFrontiers in microbiology · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jimmy Kuo *Department of Planning and Research, National Museum of Marine Biology and Aquarium, 94450, Pingtung, Taiwan.
Chin-Feng Chang *Department of Biological Science and Technology, China University of Science and Technology, 11581, Taipei, Taiwan.
Wei-Chiung ChiDepartment of Food Science, National Quemoy University, 89250, Kinmen, Taiwan. joan@email.nqu.edu.tw.ORCID http://orcid.org/0000-0001-9297-0917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal endophytes have been found to exist in many plant species and appear to be important to their plant hosts. However, the diversity and biological activities of these fungi remain largely unknown. Zanthoxylum simulans Hance, a popular natural spice and medicinal plant, commonly known as Szechuan pepper or Chinese-pepper, grows on Kinmen Island, Taiwan. In this study, leaf and stem samples of Z. simulans, collected in summer and winter, were screened for antimicrobial and anti-inflammatory metabolite-producing endophytic fungi. A total of 113 endophytic strains were isolated and cultured from Z. simulans, among which 23 were found to possess antimicrobial activity, belonging to six fungal genera: Penicillium (26.09%, 6), Colletotrichum (21.74%, 5), Diaporthe (21.74%, 5), Daldinia (17.39%, 4), Alternaria (8.70%, 2), and Didymella (4.34%, 1). We also found that the number of species with antimicrobial activity and their compositions differed between summer and winter. Our study demonstrated that Z. simulans might contain large and diverse communities of endophytic fungi, and its community composition varies seasonally. In addition, fungal endophytes produce antimicrobial agents, which may protect their hosts against pathogens and could be a potential source of natural antibiotics.

Indexed as

FungiMicrobial InteractionsPlants, MedicinalZanthoxylumAnti-Infective AgentsEndophytesAnti-Infective Agents

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.