Evidence map›Paper›PMID 33543676›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2021

Serum fibroblast growth factor 23 (FGF-23): associations with hyperphosphatemia and clinical staging of feline chronic kidney disease.

Jiabao Lin, Luqi Lin, Siyu Chen, Lifang Yu, Songjie Chen, Zhaofei Xia

Abstract read
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Dietary phosphorus and renal disease in cats: where are we?Journal of feline medicine and surgery · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiabao LinCollege of Veterinary Medicine, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0003-1910-0987
Luqi LinCollege of Veterinary Medicine, China Agricultural University, Beijing, China.
Siyu ChenCollege of Veterinary Medicine, China Agricultural University, Beijing, China.
Lifang YuVeterinary Teaching Hospital, China Agricultural University, Beijing, China.
Songjie ChenVeterinary Teaching Hospital, China Agricultural University, Beijing, China.
Zhaofei XiaCollege of Veterinary Medicine, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor 23 (FGF-23) is an independent monitor of the progression of chronic kidney disease (CKD) in human medicine, and FGF-23 may have value as a biomarker in feline CKD. We evaluated the relationship between serum FGF-23 and CKD stages, and the effect of age on FGF-23 in normal cats. We measured FGF-23 and intact parathyroid hormone (iPTH) concentrations by ELISA, with intra- and inter-assay CVs ≤ 15%. The percentage recovery of FGF-23 and iPTH remained stable for up to 7 d in samples stored at -20°C and -80°C. We measured FGF-23 in 304 cats, among which 196 were diagnosed with CKD. The 108 clinically healthy cats were divided into 5 subgroups based on growth stage (0-2 y, 3-6 y, 7-10 y, 11-14 y, ≥ 15 y). No statistical difference was found in FGF-23 among age groups (

Indexed as

AnimalsBiomarkersCat DiseasesCatsChinaFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsHyperphosphatemiaMaleParathyroid HormoneRenal Insufficiency, ChronicBiomarkersFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsParathyroid Hormonecatschronic kidney diseasefibroblast growth factor 23renal secondary hyperparathyroidism

Identifiers

PMID33543676
PMCPMC7953110

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.