Evidence map›Paper›PMID 33543438›Full record

ArticleEnvironmental science and pollution research international2021

Chemical characterization of billy goat weed extracts Ageratum conyzoides (Asteraceae) and their mosquitocidal activity against three blood-sucking pests and their non-toxicity against aquatic predators.

Venkatachalam Ramasamy, Sengodan Karthi, Raja Ganesan, Palanisamy Prakash, Sengottayan Senthil-Nathan, Subramaniam Umavathi, Patcharin Krutmuang, Prabhakaran Vasantha-Srinivasan

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. The Potentials ofInfection and drug resistance · 2023
    Review
  4. Article
  5. Article
  6. Toxicity of Bioactive Molecule Andrographolide againstMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Venkatachalam RamasamyPG and Research Department of Zoology, J.K.K. Nataraja College of Arts and Science, Komarapalayam, Tamil Nadu, 638 183, India.
Sengodan KarthiDivision of Bio-pesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tirunelveli, Tamil Nadu, 627 412, India.
Raja GanesanDepartment of Biological Science, Pusan National University, Busan, 46241, Republic of Korea.
Palanisamy PrakashDepartment of Botany, Periyar University, Periyar Palkalai Nagar, Salem, Tamil Nadu, 66 011, India.
Sengottayan Senthil-NathanDivision of Bio-pesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tirunelveli, Tamil Nadu, 627 412, India.
Subramaniam UmavathiPG and Research Department of Zoology, J.K.K. Nataraja College of Arts and Science, Komarapalayam, Tamil Nadu, 638 183, India. umajkkn@gmail.com.
Patcharin KrutmuangDepartment of Entomology and Plant Pathology, Faculty of Agriculture, Chiang Mai University, Chiang Mai, Thailand. patcharink26@gmail.com.
Prabhakaran Vasantha-SrinivasanDepartment of Biotechnology, St. Peter's Institute of Higher Education and Research, Avadi-600 054, Chennai, Tamil Nadu, India. vasanth.bmg@gmail.com.ORCID http://orcid.org/0000-0003-3415-3315
Manonmaniam Sundaranar University · INChiang Mai University · THDepartment of Biotechnology · INPeriyar University · INPusan National University · KRSt. Peter's Institute of Higher Education and Research · IN

Funding

Chiang Mai University this research work was partially supported by Chiang Mai University
6 · The paper itself

Abstract

The petroleum ether crude extracts of A. conyzoides (Pe-Ac) were used to treat three medically intimidating pests of Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus, to evaluate their non-target screening against the mosquito predator. The chemical scanning of Pe-Ac through GC-MS analysis revealed a total of nine compounds and the maximum peak area was observed in 1,5-Heptadien-3-yne (22.14%). At the maximum dosage of Pe-Ac (200 ppm), significant larvicidal activity was shown against the fourth instars of Ae. aegypti (96%), An. stephensi (93%), and Cx. quinquefasciatus (92%) respectively. The percentages of oviposition deterrence index (ODI) of all three mosquito vectors are maximum at the highest sub-lethal dosage of Pe-Ac (75 ppm) and minimum at the control dosage. The sub-lethal dosage blocked the activity of carboxylesterase activity and upregulated the detoxifying enzyme activity in a dose-dependent way. The adulticidal activity of Pe-Ac showed that the maximum adult mortality rate (100%) was recorded at the prominent dosage of Pe-Ac 600 ppm against the vectors of all three mosquitos at the maximum adulticidal time of 30 min. Histopathological investigation of fourth instar larvae of all three mosquitos treated with a sub-lethal dosage of Pe-Ac showed that the midgut cells (epithelium, lumen, and peritrophic matrix) are ruptured completely whereas they appear to be normal in control larvae. The non-toxicity evaluation of Pe-Ac compared with the chemical toxin Temephos in aquatic predator Toxorhynchites splendens revealed that the plant extracts are harmless even at the prominent dosage (1000 ppm) as compared to Temephos (1 and 2 ppm) and displayed a higher mortality rate against the mosquito predators. Thus the safety index recommends that the Pe-Ac is more explicit to targets and a suitable auxiliary to chemical pesticides.

Indexed as

AedesAgeratumAsteraceaeCulexInsecticidesAnimalsFemaleGoatsLarvaPlant ExtractsPlant LeavesInsecticidesPlant ExtractsArthropodsAsteraceaeGSTGut-lumenOvipositionPredator

Identifiers

PMID33543438
OpenAlexW3127360238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.