Evidence map›Paper›PMID 33543417›Full record

ArticleJournal of cardiovascular translational research2021

Computed Tomography Angiography for the Diagnosis of Coronary Artery Disease Among Patients Undergoing Transcatheter Aortic Valve Implantation.

David Meier, Arnaud Depierre, Antoine Topolsky, Christan Roguelov, Marion Dupré, Vladimir Rubimbura, Eric Eeckhout, Salah Dine Qanadli, Olivier Muller, Thabo Mahendiran and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiovascular translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Transcatheter aortic valve implantation in a high-risk patient with critical aortic stenosis and severe valve calcification.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Combined CT Coronary Artery Assessment and TAVI Planning.Diagnostics (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

David Meier *Department of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Arnaud Depierre *Department of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Antoine TopolskyFaculty of Biology and Medicine, Lausanne University, Lausanne, Switzerland.
Christan RoguelovDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Marion DupréDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Vladimir RubimburaDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Eric EeckhoutDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Salah Dine QanadliFaculty of Biology and Medicine, Lausanne University, Lausanne, Switzerland.
Olivier MullerDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
Thabo MahendiranDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
David RotzingerFaculty of Biology and Medicine, Lausanne University, Lausanne, Switzerland. david.rotzinger@chuv.ch.
Stephane FournierDepartment of Cardiology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland. stephane.fournier@chuv.ch.ORCID 0000-0002-0025-8162
University of Lausanne · CHFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComputed tomography angiography (CTA) is used to plan TAVI procedures. We investigated the performance of pre-TAVI CTA for excluding coronary artery disease (CAD).

methodsIn total 127 patients were included. CTA images were analyzed for the presence of ≥ 50% (significant CAD) and ≥ 70% (severe CAD) diameter stenoses in proximal coronary arteries. Results were compared with invasive coronary angiography (ICA) at vessel and patient levels. Primary endpoint was the negative predictive value (NPV) of CTA for the presence of CAD.

resultsA total of 342 vessels were analyzable. NPV of CTA was 97.5% for significant CAD and 96.3% for severe CAD. Positive predictive value and accuracy were 44.8% and 87.1% for significant CAD and 56.3% and 94.4% for severe CAD. At patient level, NPV for significant CAD was 88.6%.

conclusionPre-TAVI CTA shows good performance for ruling out CAD and could be used as a gatekeeper for ICA in selected patients.

Indexed as

Coronary Artery DiseaseTranscatheter Aortic Valve ReplacementComputed Tomography AngiographyCoronary AngiographyHumansRetrospective StudiesAortic valve stenosisComputed tomography angiographyCoronary artery diseaseTranscatheter aortic valve implantation

Identifiers

PMID33543417
PMCPMC8575747
OpenAlexW3128235271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.