Evidence map›Paper›PMID 33543393›Full record

ArticleAnnals of nuclear medicine2021

Prediction of local recurrence and distant metastasis using radiomics analysis of pretreatment nasopharyngeal [18F]FDG PET/CT images.

Lihong Peng, Xiaotong Hong, Qingyu Yuan, Lijun Lu, Quanshi Wang, Wufan Chen

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Article in Annals of nuclear medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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  12. Clinical application ofJapanese journal of radiology · 2024
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  17. [Research progress in CT-based radiomics constructing hypopharyngeal cancer and multisystem tumor prediction model].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lihong Peng *School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xiaotong Hong *School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Qingyu YuanNanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Lijun LuSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, Guangdong, China. ljlubme@gmail.com.ORCID http://orcid.org/0000-0002-7001-4892
Quanshi WangNanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. wangquanshiwl@126.com.
Wufan ChenSchool of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, Guangdong, China. chenwf@smu.edu.cn.
Southern Medical University · CNNanfang Hospital · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2019A1515011104Guangdong Province Higher Vocational Colleges and Schools Pearl River Scholar Funded Scheme (CN) Lijun Lu, 2018National Natural Science Foundation of China 81871437
6 · The paper itself

Abstract

objectivesTo develop a radiomics signature to predict locoregional recurrence (LR) and distant metastasis (DM), as extracted from pretreatment 2-deoxy-2-[ MATERIALS AND

methodsEighty-five patients with Stage III-IVB NPC underwent pretreatment [

resultsTwenty features had significant differences between disease control and treatment failure. NPC patients with values of Compactness1, Compactness2, Coarseness_NGTDM or SGE_GLGLM above the median as well as patients with values of Irregularity, RLN_GLRLM or GLV_GLSZM below the median, showed a significant (p < 0.05) higher risk of treatment failure (about 50% vs. 25%). The derived radiomics signature consisted of 5 features with the highest AUC value of 0.8290 (sensitivity: 0.8438, specificity: 0.7736) using leave-one-out-cross-validation.

conclusionLocoregional recurrence (LR) and DM of locally advanced NPC can be predicted using radiomics analysis of pretreatment [

Indexed as

AdolescentAdultAgedAge FactorsAlgorithmsChemoradiotherapyFemaleFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedMaleMiddle AgedMultivariate AnalysisNeoplasm MetastasisNeoplasm Recurrence, LocalPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18Radiopharmaceuticals[18F]FDG PET/CTNasopharyngeal carcinomaPrognosisRadiomics

Identifiers

PMID33543393
OpenAlexW3126540680

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.