Evidence map›Paper›PMID 33543259›Full record

Observational studyEuropean heart journal2021

Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation.

Pedram Sultanian, Peter Lundgren, Anneli Strömsöe, Solveig Aune, Göran Bergström, Eva Hagberg, Jacob Hollenberg, Jonny Lindqvist, Therese Djärv, Albert Castelheim and 10 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 6 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 6 syntheses or guidelines pooled it, 131 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Pedram SultanianUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Peter LundgrenUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Anneli StrömsöeCentre for Clinical Research Dalarna, Uppsala University, S-79182 Falun, Sweden.
Solveig AuneUnit for Health Care Coordination, Head Office, Region Västra Götaland, Sweden.
Göran BergströmUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Eva HagbergRegion Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, Gothenburg, Sweden.
Jacob HollenbergDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Jonny LindqvistUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Therese DjärvDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Albert CastelheimUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Anna ThorénDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Fredrik HessulfDepartment of Anesthesiology and Intensive Care Medicine, Halland Hospital, Halmstad, Sweden.
Leif SvenssonDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Andreas ClaessonDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Hans FribergLund University, Skane University Hospital, Department of Clinical Sciences, Anesthesia & Intensive Care, Malmö, Sweden.
Per NordbergDepartment of Medicine, Centre for Resuscitation Science, Karolinska Institutet, Solna, Sweden.
Elmir OmerovicUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Annika RosengrenUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Johan HerlitzUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
Araz RawshaniUniversity of Gothenburg, Institute of Medicine, Department of Molecular and Clinical Medicine, Gothenburg, Sweden.
University of Gothenburg · SEKarolinska Institutet · SEHallands sjukhus Halmstad · SELund University · SERegion Västra Götaland · SESahlgrenska University Hospital · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the characteristics and outcome among cardiac arrest cases with COVID-19 and differences between the pre-pandemic and the pandemic period in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). METHOD AND

resultsWe included all patients reported to the Swedish Registry for Cardiopulmonary Resuscitation from 1 January to 20 July 2020. We defined 16 March 2020 as the start of the pandemic. We assessed overall and 30-day mortality using Cox regression and logistic regression, respectively. We studied 1946 cases of OHCA and 1080 cases of IHCA during the entire period. During the pandemic, 88 (10.0%) of OHCAs and 72 (16.1%) of IHCAs had ongoing COVID-19. With regards to OHCA during the pandemic, the odds ratio for 30-day mortality in COVID-19-positive cases, compared with COVID-19-negative cases, was 3.40 [95% confidence interval (CI) 1.31-11.64]; the corresponding hazard ratio was 1.45 (95% CI 1.13-1.85). Adjusted 30-day survival was 4.7% for patients with COVID-19, 9.8% for patients without COVID-19, and 7.6% in the pre-pandemic period. With regards to IHCA during the pandemic, the odds ratio for COVID-19-positive cases, compared with COVID-19-negative cases, was 2.27 (95% CI 1.27-4.24); the corresponding hazard ratio was 1.48 (95% CI 1.09-2.01). Adjusted 30-day survival was 23.1% in COVID-19-positive cases, 39.5% in patients without COVID-19, and 36.4% in the pre-pandemic period.

conclusionDuring the pandemic phase, COVID-19 was involved in at least 10% of all OHCAs and 16% of IHCAs, and, among COVID-19 cases, 30-day mortality was increased 3.4-fold in OHCA and 2.3-fold in IHCA.

Indexed as

AgedAged, 80 and overCardiopulmonary ResuscitationCOVID-19FemaleHeart ArrestHumansMaleMiddle AgedOut-of-Hospital Cardiac ArrestRegistriesSurvival RateSwedenCardiac arrestCOVID-19

Identifiers

PMID33543259
PMCPMC7928992
OpenAlexW3127261778

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.