ArticleNeuro-oncology advances
The long-term caregiver burden in World Health Organization grade I and II meningioma: It is not just the patient.
Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- "Chipped but not broken" - patients' symptoms and challenges beyond five years post radiotherapy for meningioma: a qualitative interview study.BMC neurology · 2026Article
- A Scoping Review of Exercise Oncology in the Primary Brain Tumor Patient-Caregiver Dyad.Current oncology (Toronto, Ont.) · 2026Article
- The CARING intervention for neuro-oncology family caregivers: Primary outcomes from an abbreviated randomized controlled trial.Neuro-oncology practice · 2026Article
- The CARING intervention for neuro-oncology family caregivers: Randomized controlled trial feasibility, eSNAP/caregiver navigation engagement, and acceptability.Neuro-oncology practice · 2025Article
- Health-Related Quality of Life and Treatment Satisfaction of Patients with Malignant IDH Wild-Type Gliomas and Their Caregivers.Current oncology (Toronto, Ont.) · 2024Article
- The experience of caregiving for adults with benign brain tumors: An integrative review.Neuro-oncology practice · 2024Review
- Cognition and health-related quality of life in long-term survivors of high-grade glioma: an interactive perspective from patient and caregiver.Acta neurochirurgica · 2024Article
- 'A Constant Black Cloud': The Emotional Impact of Informal Caregiving for Someone With a Lower-Grade Glioma.Qualitative health research · 2024Article
- Unmet needs and wish for support of family caregivers of primary brain tumor patients.Neuro-oncology practice · 2023Article
- Status and influencing factors of disease uncertainty among family caregivers of patients with moderate and severe craniocerebral injury: a quantitative and qualitative study.Acta neurochirurgica · 2022Article
- Measuring everyday functioning in patients with brain tumor: The long rows yet to hoe.Neuro-oncology practice · 2022Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about long-term caregiver burden in meningioma patients. We assessed meningioma caregiver burden, its association with informal caregiver's well-being and possible determinants.
methodsIn this multicenter cross-sectional study, informal caregivers completed the Caregiver Burden Scale (five domains and total score). Patients completed a disease-specific health-related quality of life (HRQoL) questionnaire focusing on symptoms (EORTC QLQ-BN20) and underwent neurocognitive assessment. Both groups completed a generic HRQoL questionnaire (SF-36) and the Hospital Anxiety, and Depression Scale. We assessed the association between caregiver burden and their HRQoL, anxiety and depression. Furthermore, we assessed determinants for the caregiver burden. Multivariable regression analysis was used to correct for confounders.
resultsOne hundred and twenty-nine informal caregivers were included (median 10 years after patients' treatment). Caregivers reported burden in ≥1 domain (34%) or total burden score (15%). A one-point increase in total caregiver burden score was associated with a clinically relevant decrease in caregiver's HRQoL (SF-36) in 5/8 domains (score range: -10.4 to -14.7) and 2/2 component scores (-3.5 to -5.9), and with more anxiety (3.8) and depression (3.0). Patients' lower HRQoL, increased symptom burden, and increased anxiety and depression were determinants for higher caregiver burden, but not patients' or caregivers' sociodemographic characteristics, patients' neurocognitive functioning, or tumor- and treatment-related characteristics.
conclusionsTen years after initial treatment, up to 35% of informal caregivers reported a clinically relevant burden, which was linked with worse HRQoL, and more anxiety and depression in both patients and caregivers, emphasizing the strong interdependent relationship. Support for meningioma caregivers is therefore warranted.
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