Evidence map›Paper›PMID 33543021›Full record

ArticleMatrix biology plus2020

Collagen XV, a multifaceted multiplexin present across tissues and species.

Sandrine Bretaud, Emilie Guillon, Sanna-Maria Karppinen, Taina Pihlajaniemi, Florence Ruggiero

Abstract read
In one paragraph

Article in Matrix biology plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
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  9. Article
  10. Review
  11. The Role ofCancers · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Collagen VIII in vascular diseases.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Dual topologies of myotomal collagen XV and Tenascin C act in concert to guide and shape developing motor axons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandrine BretaudInstitut de Génomique Fonctionnelle de Lyon, ENS de Lyon, UMR CNRS 5242, University of Lyon, Lyon 69364, France.
Emilie GuillonInstitut de Génomique Fonctionnelle de Lyon, ENS de Lyon, UMR CNRS 5242, University of Lyon, Lyon 69364, France.
Sanna-Maria KarppinenCenter for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7C, FI-90230 Oulu, Finland.
Taina PihlajaniemiCenter for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7C, FI-90230 Oulu, Finland.
Florence RuggieroInstitut de Génomique Fonctionnelle de Lyon, ENS de Lyon, UMR CNRS 5242, University of Lyon, Lyon 69364, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type XV collagen is a non-fibrillar collagen that is associated with basement membranes and belongs to the multiplexin subset of the collagen superfamily. Collagen XV was initially studied because of its sequence homology with collagen XVIII/endostatin whose anti-angiogenic and anti-tumorigenic properties were subjects of wide interest in the past years. But during the last fifteen years, collagen XV has gained growing attention with increasing number of studies that have attributed new functions to this widely distributed collagen/proteoglycan hybrid molecule. Despite the cumulative evidence of its functional pleiotropy and its evolutionary conserved function, no review compiling the current state of the art about collagen XV is currently available. Here, we thus provide the first comprehensive view of the knowledge gathered so far on the molecular structure, tissue distribution and functions of collagen XV in development, tissue homeostasis and disease with an evolutionary perspective. We hope that our review will open new roads for promising research on collagen XV in the coming years.

Indexed as

Animal modelsBM, basement membraneBMZ, basement membrane zoneCOL, collagenous domainCollagen-related diseaseCollagensCS, chondroitin sulfateCSPG, chondroitin sulfate proteoglycanDevelopmentdpf, day post-fertilizationECM, extracellular matrixEvolutionExtracellular matrixGAG, glycosaminoglycanHFD, High fat dietHS, heparan sulfateHSPG, heparan sulfate proteoglycanMultiplexinNC, non-collagenous domainTD, trimerization domainTSPN, Thrombospondin-1 N-terminal like domain

Identifiers

PMID33543021
PMCPMC7852327

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.