Evidence map›Paper›PMID 33542864›Full record

ArticleCureus2021

Balkan Endemic Nephropathy: An Autopsy Case Report.

George S Stoyanov, Ina Kobakova, Lilyana Petkova, Deyan L Dzhenkov, Hristo Popov

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

George S StoyanovGeneral and Clinical Pathology/Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Ina KobakovaGeneral and Clinical Pathology/Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Lilyana PetkovaGeneral and Clinical Pathology/Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Deyan L DzhenkovGeneral and Clinical Pathology/Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Hristo PopovGeneral and Clinical Pathology/Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.
Medical University of Varna · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balkan endemic nephropathy (BEN) is a form of interstitial nephritis seen only in certain geographical areas in the Balkan peninsula. Herein we describe the gross and histological changes in a diseased 42-year-old male Caucasian patient with BEN. All the changes fit the classically described alterations, with copper hue discoloration of the skin of the torso and orange discoloration of the soles and palms. Grossly, the kidneys were atrophic, with the left one weighing 31 grams and the right one 32 grams. Their surface was predominantly smooth with areas of fine granulations and cystic transformations. Histology revealed hyalinization of the glomeruli, predominantly in the external part of the cortex, severe vascular changes, interstitial fibrosis, and scant inflammatory cell infiltrate. The renal pelvis and ureters revealed multiple urothelial papillomas and atypical urothelial hyperplasia. BEN is only one geographical variant of interstitial nephritis caused by exposure to aristolochic acid. Other forms of this condition include Chinese herb nephropathy/aristolochic acid nephropathy, as well as several similar endemic conditions with a yet unestablished link to aristolochic acid.

Indexed as

balkan endemic nephropathyhistologyinterstitial nephritispathology

Identifiers

PMID33542864
PMCPMC7847780
OpenAlexW3115769924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.