ArticleOxidative medicine and cellular longevity2021
Effects of Occupational Exposure to Waste Anesthetic Gas on Oxidative Stress and DNA Damage.
Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Occupational Exposure to Inhalation Anesthetics in Operating Room and Adverse Health Outcomes: A Systematic Review.La Medicina del lavoro · 2026Pooled it
- Genetic biomarkers and individual susceptibility in healthcare workers exposed to waste anesthetic gases: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Occupational exposure to inhalational anesthetics and the risk of spontaneous abortion: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Exploratory microbiota-metabolite alterations associated with cognitive impairment after repeated low-dose sevoflurane exposure in mice.Frontiers in cellular and infection microbiology · 2026Article
- A multianalyte method for simultaneous evaluation of occupational exposure to anesthetic gases in urine samples from healthcare professionals.Frontiers in public health · 2026Article
- Invasive ventilator exhaust in critical care: aerosol transmission risks and management strategies-a narrative review.Critical care (London, England) · 2025Review
- Morphometric analysis of the female reproductive tract: influence of long-term inhalation of trace amounts of sevoflurane.Journal of molecular histology · 2024Article
- Monitoring of liver and kidney profiles in anesthesiologists working in a regional reference teaching hospital in Northern Italy: analysis of health surveillance data using a linear mixed model.International journal of occupational medicine and environmental health · 2024Article
- Bibliometric analysis of occupational exposure in operating room from 1973 to 2022.Journal of occupational medicine and toxicology (London, England) · 2024Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to investigate the potential effects of waste anesthetic gas (WAG) on oxidative stress, DNA damage, and vital organs.
methodsA total of 150 members of the staff at a hospital were assigned to an exposure group or control group. The 68 operating room (OR) staff in the exposure group were exposed to WAG, and the 82 non-OR staff in the control group were not exposed to WAG. Air samples were collected in the OR, and the sevoflurane concentrations in the samples were determined. Superoxide dismutase (SOD), glutathione peroxidase (GSH-px), and malondialdehyde (MDA) in plasma from the participants were determined to assess oxidative stress. Western blot analysis was used to detect
resultsThe mean (±standard deviation) sevoflurane concentration in 172 air samples from 22 operating rooms was 1.11 ± 0.65 ppm. The superoxide dismutase activity and vital organ parameters (lymphocyte, hemoglobin, and total protein concentrations and heart rate) were significantly lower (
conclusionsLong-term occupational exposure to waste anesthetic gas may affect the antioxidant defense system and probably affects vital organ functions to some extent. No correlation between DNA damage and chronic exposure to WAG was observed.
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