Evidence map›Paper›PMID 33542675›Full record

ArticleMediators of inflammation2021

Yeast Fermentate Prebiotic Ameliorates Allergic Asthma, Associating with Inhibiting Inflammation and Reducing Oxidative Stress Level through Suppressing Autophagy.

Subo Gong, Xiaoying Ji, Jing Su, Yina Wang, Xianghong Yan, Guyi Wang, Bin Xiao, Haiyun Dong, Xudong Xiang, Shaokun Liu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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  9. Aerosol Inhalation of Heat-KilledJournal of immunology research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Subo GongSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Xiaoying JiPulmonary and Critical Care Medicine, The Seventh Affiliated Hospital, Sun Yat-sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming District, Shenzhen City, China.
Jing SuSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Yina WangSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Xianghong YanDepartment of Laboratory Medicine, Changsha Central Hospital, Nanhua University, Changsha City, Hunan Province, China.
Guyi WangSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Bin XiaoSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Haiyun DongSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Xudong XiangSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.
Shaokun LiuSecond Xiangya Hospital of Central South University, No. 139 Middle Renmin Road, Changsha City, Hunan Province, China.ORCID https://orcid.org/0000-0002-9839-2342
Central South University · CNChangsha Central Hospital · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsOvalbumin was used to induce allergic asthma following administration of YFP for one week in mice, to collect the lung tissues, bronchoalveolar lavage fluid (BLFA), and feces. The pathological state, tight-junction proteins, inflammatory and oxidative stress-associated biomarkers, and TLRs/NF-

resultYFP ameliorated the lung injury of the mouse asthma model by inhibiting peribronchial and perivascular infiltrations of eosinophils and increasing tight-junction protein expression. YFP inhibited the decrease in the number of BALF leukocytes and expression of inflammatory-related genes and reversed OVA-induced TLRs/NF-

conclusionOur research showed that YFP might exert antiasthmatic effects by inhibiting airway allergic inflammation and oxidative stress level through suppressing autophagy.

Indexed as

AutophagyFermentationOxidative StressPrebioticsAnimalsAnti-Asthmatic AgentsAsthmaBiomarkersBronchoalveolar Lavage FluidDNA, RibosomalInflammationLungMaleMiceMice, Inbred BALB CSequence Analysis, DNAAnti-Asthmatic AgentsBiomarkersDNA, RibosomalPrebiotics

Identifiers

PMID33542675
PMCPMC7840264
OpenAlexW3121820502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.