Evidence map›Paper›PMID 33542657›Full record

ArticleCancer management and research2021

Primary Squamous Cell Carcinoma of the Liver is Rare but Hostile: Case Series and Comprehensive Review of the Literature.

Junjuan Xiao, Lin Ma, Junwei Li, Beibei Yin, Jing Liang, Jun Wang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Primary Hepatic Squamous Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Primary Squamous Cell Carcinoma of the Liver.European journal of case reports in internal medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Primary squamous cell carcinoma of the liver: a case report.Gastroenterology and hepatology from bed to bench · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Junjuan XiaoDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Lin MaDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Junwei LiDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Beibei YinDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Jing LiangDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.ORCID 0000-0003-3252-7563
Jun WangDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, People's Republic of China.
Shandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary squamous cell carcinoma (SCC) of the liver is an uncommon cancer type. Only dozens of such cases have been reported in the literature. We reviewed three cases with primary SCC of the liver in a single center from January 2013 to October 2019. One case was positive for hepatitis B infection and simultaneously diagnosed with sigmoid adenocarcinoma and liver cyst. The second patient presented with hepatolithiasis. The remaining one had no history of prior liver insult, hepatic infection or any pre-existing hepatic cysts. Two cases had a long survival of more than one year through chemotherapy, or radical surgery plus transarterial chemoembolization. We also found 25 patients with primary hepatic SCC in the Surveillance, Epidemiology and End Results (SEER) database from 1997 to 2016. The median age was 67 years (range 33-87 years). The median overall survival and disease-specific survival were 7.7 months (range 0.0-76.0 months) and 2.0 months (range 0.0-20.0 months), respectively. Furthermore, patients receiving surgery had a longer median OS (20.0 versus 6.0 months,

Indexed as

chemotherapyliverprimary squamous cell carcinomaSEERsurgerysurvival

Identifiers

PMID33542657
PMCPMC7853432
OpenAlexW3196334324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.