Evidence map›Paper›PMID 33542627›Full record

ArticleInternational journal of nanomedicine2021

Nanostructured Coating of Non-Crystalline Tantalum Pentoxide on Polyetheretherketone Enhances RBMS Cells/HGE Cells Adhesion.

Zhiying Pang, Zhangyi Pan, Min Ma, Zhiyan Xu, Shiqi Mei, Zengxin Jiang, Feng Yin

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Improving iPSC Differentiation Using a Nanodot Platform.ACS applied materials & interfaces · 2024
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  4. Review
  5. Review
  6. Chemically heparinized PEEKRSC advances · 2024
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhiying Pang *Department of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, People's Republic of China.
Zhangyi Pan *Department of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, People's Republic of China.
Min MaDepartment of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, People's Republic of China.
Zhiyan XuKey Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, People's Republic of China.
Shiqi MeiKey Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, People's Republic of China.
Zengxin JiangDepartment of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, People's Republic of China.
Feng YinDepartment of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, People's Republic of China.
Shanghai East Hospital · CNEast China University of Science and Technology · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs a dental material, polyetheretherketone (PEEK) is bioinert that does not induce cellular response and bone/gingival tissues regeneration. This study was to develop bioactive coating on PEEK and investigate the effects of coating on cellular response. MATERIALS AND

methodsTantalum pentoxide (TP) coating was fabricated on PEEK surface by vacuum evaporation and responses of rat bone marrow mesenchymal stem (RBMS) cells/human gingival epithelial (HGE) were studied.

resultsA dense coating (around 400 nm in thickness) of TP was closely combined with PEEK (PKTP). Moreover, the coating was non-crystalline TP, which contained many small humps (around 10 nm in size), exhibiting a nanostructured surface. In addition, the roughness, hydrophilicity, surface energy, and protein adsorption of PKTP were remarkably higher than that of PEEK. Furthermore, the responses (adhesion, proliferation, and osteogenic gene expression) of RBMS cells, and responses (adhesion and proliferation) of HGE cells to PKTP were remarkably improved in comparison with PEEK. It could be suggested that the nanostructured coating of TP on PEEK played crucial roles in inducing the responses of RBMS/HGE cells.

conclusionPKTP with elevated surface performances and outstanding cytocompatibility might have enormous potential for dental implant application.

Indexed as

AdsorptionAlkaline PhosphataseAnimalsBenzophenonesCell AdhesionCell ProliferationCell ShapeEpithelial CellsGene Expression RegulationGingivaHumansHydrophobic and Hydrophilic InteractionsKetonesMaleMesenchymal Stem CellsNanostructuresAlkaline PhosphataseBenzophenonesKetonesOxidespolyetheretherketonePolyethylene GlycolsPolymersTantalumtantalum oxidecytocompatibilitydental implant applicationsnanostructured coatingpolyetheretherketonetantalum pentoxide

Identifiers

PMID33542627
PMCPMC7853447
OpenAlexW3125594308

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.