Evidence map›Paper›PMID 33542344›Full record

ArticleScientific reports2021

Theta-modulated oscillatory transcranial direct current stimulation over posterior parietal cortex improves associative memory.

Katarina Vulić, Jovana Bjekić, Dunja Paunović, Miloš Jovanović, Slađan Milanović, Saša R Filipović

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  20. Brain activity patterns underlying memory confidence.The European journal of neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katarina VulićDepartment for Human Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia. katarina.vulic@imi.bg.ac.rs.
Jovana BjekićDepartment for Human Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Dunja PaunovićDepartment for Human Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Miloš JovanovićThe School of Computing, Union University, Belgrade, Serbia.
Slađan MilanovićDepartment for Biomedical Engineering and Biophysics, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Saša R FilipovićDepartment for Human Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Associative memory (AM) reflects the ability to remember and retrieve multiple pieces of information bound together thus enabling complex episodic experiences. Despite growing interest in the use of transcranial direct current stimulation (tDCS) for the modulation of AM, there are inconsistent evidence regarding its benefits. An alternative to standard constant tDCS could be the application of frequency-modulated tDCS protocols, that mimic natural function-relevant brain rhythms. Here, we show the effects of anodal tDCS oscillating in theta rhythm (5 Hz; 1.5 ± 0.1 mA) versus constant anodal tDCS and sham over left posterior parietal cortex on cued recall of face-word associations. In a crossover design, each participant completed AM assessment immediately following 20-min theta-oscillatory, constant, and sham tDCS, as well as 1 and 5 days after. Theta oscillatory tDCS increased initial AM performance in comparison to sham, and so did constant tDCS. On the group level, no differences between oscillatory and constant tDCS were observed, but individual-level analysis revealed that some participants responded to theta-oscillatory but not to constant tDCS, and vice versa, which could be attributed to their different physiological modes of action. This study shows the potential of oscillatory tDCS protocols for memory enhancement to produce strong and reliable memory-modulating effects which deserve to be investigated further.

Indexed as

AdultCognitionFemaleHumansMaleMemoryMental RecallParietal LobePrefrontal CortexTheta RhythmTranscranial Direct Current StimulationYoung Adult

Identifiers

PMID33542344
PMCPMC7862221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.