Evidence map›Paper›PMID 33542311›Full record

ArticleScientific reports2021

Identifying the signature of prospective motor control in children with autism.

Andrea Cavallo, Luca Romeo, Caterina Ansuini, Francesca Battaglia, Lino Nobili, Massimiliano Pontil, Stefano Panzeri, Cristina Becchio

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Motor Disorders in Autism: From Comorbidity to Core Criterion.Autism research : official journal of the International Society for Autism Research · 2026
    Review
  3. Reduced Hand Specialization and Idiosyncratic Visuomotor Strategies in Autism During Naturalistic Object Manipulation.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  4. Reduced Dissociation Between Perception and Action in Autistic Individuals.Journal of autism and developmental disorders · 2026
    Article
  5. Article
  6. Motor organisation of social play in children with autism.Journal of the Royal Society, Interface · 2025
    Article
  7. Review
  8. Effective Autism Classification Through Grasping Kinematics.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Intersecting kinematic encoding and readout of intention in autism.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Andrea CavalloCognition, Motion and Neuroscience Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy.
Luca RomeoDepartment of Information Engineering, Università Politecnica delle Marche, Ancona, Italy.
Caterina AnsuiniCognition, Motion and Neuroscience Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy.
Francesca BattagliaCognition, Motion and Neuroscience Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy.
Lino NobiliChild Neuropsychiatric Unit, IRCCS Istituto G. Gaslini, Genoa, Italy.
Massimiliano PontilComputational Statistics and Machine Learning Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy.
Stefano PanzeriNeural Computational Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy.
Cristina BecchioCognition, Motion and Neuroscience Laboratory, Center for Human Technologies, Istituto Italiano di Tecnologia, Genoa, Italy. cristina.becchio@iit.it.
Italian Institute of Technology · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMarche Polytechnic University · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Failure to develop prospective motor control has been proposed to be a core phenotypic marker of autism spectrum disorders (ASD). However, whether genuine differences in prospective motor control permit discriminating between ASD and non-ASD profiles over and above individual differences in motor output remains unclear. Here, we combined high precision measures of hand movement kinematics and rigorous machine learning analyses to determine the true power of prospective movement data to differentiate children with autism and typically developing children. Our results show that while movement is unique to each individual, variations in the kinematic patterning of sequential grasping movements genuinely differentiate children with autism from typically developing children. These findings provide quantitative evidence for a prospective motor control impairment in autism and indicate the potential to draw inferences about autism on the basis of movement kinematics.

Indexed as

Autism Spectrum DisorderBiomechanical PhenomenaCase-Control StudiesChildFemaleHandHand StrengthHumansMachine LearningMaleMovementPsychomotor Performance

Identifiers

PMID33542311
PMCPMC7862688
OpenAlexW3127297076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.