ArticleScientific reports2021
Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.The Cochrane database of systematic reviews · 2022Pooled it
- Review
- Evolving infectious disease dynamics shape school-based intervention effectiveness.Nature communications · 2025Article
- Aging shapes infection profiles of influenza A virus and SARS-CoV-2 in human precision-cut lung slices.Respiratory research · 2025Article
- Testing for SARS-CoV-2: lessons learned and current use cases.Clinical microbiology reviews · 2024Review
- SARS-CoV-2 variant with the spike protein mutation F306L in the southern border provinces of Thailand.Scientific reports · 2024Article
- Epidemiology of the SARS-CoV-2 Omicron Variant Emergence in the Southeast Brazilian Population.Microorganisms · 2024Article
- Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown.Advances in virology · 2024Article
- SARS-CoV-2 viral load and shedding kinetics.Nature reviews. Microbiology · 2023Review
- Relationship between viral load and symptoms in children infected with SARS-CoV-2.Pediatric research · 2023Article
- The Diagnostic Accuracy of SARS-CoV-2 Nasal Rapid Antigen Self-Test: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2023Review
- Are SARS-CoV-2 viral loads in children lower than in adults?The Journal of infection · 2023Article
- Challenges of vaccination and herd immunity in COVID-19 and management strategies.The clinical respiratory journal · 2022Review
- High Prevalence of Undocumented SARS-CoV-2 Infections in the Pediatric Population of the Tyrolean District of Schwaz.Viruses · 2022Article
- Favorable Outcome in Infants Hospitalized With COVID-19: Single Center Experience from Athens, Greece.Indian pediatrics · 2022Article
- Simulating respiratory disease transmission within and between classrooms to assess pandemic management strategies at schools.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- COVID-19 and children.Science (New York, N.Y.) · 2022Article
- Upper airway gene expression shows a more robust adaptive immune response to SARS-CoV-2 in children.Nature communications · 2022Article
- The SARS-CoV-2 pandemic in Germany may represent the sum of a large number of local but independent epidemics each initiated by individuals aged 10-19 years, middle-aged males, or elderly individuals.Journal of medical virology · 2022Article
- Cellular, Antibody and Cytokine Pathways in Children with Acute SARS-CoV-2 Infection and MIS-C-Can We Match the Puzzle?Antibodies (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
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Registered trials
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