Evidence map›Paper›PMID 33542006›Full record

ArticleBMJ case reports2021

Atraumatic trismus induced by duloxetine: an uncommon presentation of acute dystonia.

May Honey Ohn, Jiann Lin Loo, Khin Maung Ohn

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

May Honey OhnEmergency Department, Sandwell General Hospital, West Midlands, West Bromwich, UK.ORCID http://orcid.org/0000-0002-1951-6598
Jiann Lin LooPsychiatry Department, Central and North West London NHS Foundation Trust, Eaglestone, Milton Keynes, UK.ORCID http://orcid.org/0000-0001-5620-924X
Khin Maung OhnSurgery Department, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia drkmgohn@ums.edu.my.
Central and North West London NHS Foundation Trust · GBSandwell General Hospital · GBUniversiti of Malaysia Sabah · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atraumatic trismus can be one of the presentations of medication-induced acute dystonia, particularly by antipsychotics and less commonly antidepressants. A case of an unusual emergency presentation of atraumatic trismus on initiation of duloxetine is reported. The patient was a 40-year-old woman experiencing sudden difficulty in mouth opening and speaking due to a stiffened jaw after taking 5 days of duloxetine prescribed for her fibromyalgia-related chest pain. Assessment of vital signs is prudent to ensure there is no laryngeal involvement. Other physical examinations and her recent investigations were unremarkable. She was treated for acute dystonia and intravenous procyclidine was given together with oral diazepam. Her symptoms improved immediately and her duloxetine was suggested to be stopped. To our knowledge, this is the first case of isolated trismus induced by duloxetine. Clinicians should be aware of this risk, especially considering the limitation of important physiological functions (such as swallowing, eating, etc) associated with this condition.

Indexed as

Antidepressive AgentsDuloxetine HydrochlorideAdultAntiparkinson AgentsAntipsychotic AgentsDystoniaFemaleFibromyalgiaHumansProcyclidineTrismusAntidepressive AgentsAntiparkinson AgentsAntipsychotic AgentsDuloxetine HydrochlorideProcyclidineMedical managementPsychiatry (drugs and medicines)Unwanted effects / adverse reactions

Identifiers

PMID33542006
PMCPMC7868243
OpenAlexW3128760880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.